Evidence map›Paper›PMID 40327229›Full record

ArticleDiscover oncology2025

Global trends and research status in clonal hematopoiesis: a bibliometric analysis of the last 10 years.

QingQing Luo, Li Yu

Abstract read
In one paragraph

Article in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

QingQing LuoDepartment of Hematology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Jiangxi Provincial Key Laboratory of Hematological Diseases (2024SSY06052), Nanchang, Jiangxi, China.
Li YuDepartment of Hematology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Jiangxi Provincial Key Laboratory of Hematological Diseases (2024SSY06052), Nanchang, Jiangxi, China. ndefy02021@ncu.edu.cn.

Funding

Major Discipline Academic and Technical Leaders Training Program of Jiangxi Province 20225BCJ22001National Natural Science Foundation of China 82260043Natural Science Foundation of Jiangxi Province 20232ACB206016, 20204BCJ22030
6 · The paper itself

Abstract

objectiveClonal hematopoiesis (CH) refers to the clonal expansion of hematopoietic stem cells caused by somatic mutations. CH is commonly observed in elderly individuals and is closely associated with myeloid malignancies as well as various non-malignant diseases. This study aims to explore the research trends and hotspots of CH using bibliometric analysis.

methodsRelevant studies were retrieved from the Web of Science Core Collection database based on predefined inclusion criteria. Bibliometric analysis and visualization were conducted using VOSviewer, CiteSpace, and R software.

resultsA total of 851 studies were included. From 2014 to 2024, the annual number of publications showed a consistent upward trend. The United States was identified as the leading country in this field, contributing 53.7% of the total publications. Harvard Medical School and Benjamin L Ebert were recognized as the most influential institution and author, respectively. Blood was the most prolific journal, with the highest citation and H-index. Research on CH-related gene mutations and their association with the risk of acute myeloid leukemia is currently the most extensively studied area, while cardiovascular diseases and inflammation have emerged as recent research hotspots.

conclusionThis study is the first to systematically analyze research related to CH using bibliometric methods. Our analysis reveals the overall landscape of CH research and identifies the most influential contributors in the field, including countries, institutions, authors, and journals. Moreover, we identify emerging research hotspots and key areas, highlighting potential avenues for exploration and innovation within the field of CH.

Indexed as

BibliometricClonal hematopoiesisResearch hotspotsResearch trendVisualized

Identifiers

PMID40327229
PMCPMC12055686

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.