Evidence map›Paper›PMID 40327221›Full record

ArticleJournal of ophthalmic inflammation and infection2025

Fulminant endophthalmitis after open globe injury by cat claw: two case reports and literature review.

Ashley Y Gao, Ameay V Naravane, Michael A Simmons, Tyler Looysen, Sandra Montezuma, Dara Koozekanani, Hossein Nazari

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In one paragraph

Article in Journal of ophthalmic inflammation and infection, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Ashley Y GaoDepartment of Ophthalmology and Visual Neuroscience, University of Minnesota, 516 Delaware Street SE, 9-337, Minneapolis, MN, 55455, USA.
Ameay V NaravaneDepartment of Ophthalmology and Visual Neuroscience, University of Minnesota, 516 Delaware Street SE, 9-337, Minneapolis, MN, 55455, USA.
Michael A SimmonsDepartment of Ophthalmology and Visual Neuroscience, University of Minnesota, 516 Delaware Street SE, 9-337, Minneapolis, MN, 55455, USA.
Tyler LooysenDepartment of Ophthalmology and Visual Neuroscience, University of Minnesota, 516 Delaware Street SE, 9-337, Minneapolis, MN, 55455, USA.
Sandra MontezumaDepartment of Ophthalmology and Visual Neuroscience, University of Minnesota, 516 Delaware Street SE, 9-337, Minneapolis, MN, 55455, USA.
Dara KoozekananiDepartment of Ophthalmology and Visual Neuroscience, University of Minnesota, 516 Delaware Street SE, 9-337, Minneapolis, MN, 55455, USA.
Hossein NazariDepartment of Ophthalmology and Visual Neuroscience, University of Minnesota, 516 Delaware Street SE, 9-337, Minneapolis, MN, 55455, USA. nazari@umn.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe two patients with fulminant endophthalmitis after penetrating ocular injuries by cat claw and review the literature regarding animal-related endophthalmitis.

designCase series.

participantsIn the study period, 298 patients were identified with a diagnosis of endophthalmitis, of which two were identified in association with open globe injury by cat claw.

methodsAll patients with endophthalmitis after cat claw open globe injury in an academic center in a 20-year period are reported. Clinical and laboratory presentations, medical and surgical treatment, and outcomes are described. A literature review is summarized. EXPOSURE: Open globe injury by cat claw.

main outcome measuresInterventions and ocular anatomical and functional outcomes.

resultsCase 1: A 27-year-old female sustained a penetrating injury of the left eye by a cat claw. The laceration was repaired the next day, and intravitreal antibiotics injections were given. She developed acute fulminant endophthalmitis the following day and underwent pars plana vitrectomy, anterior chamber washout, and intravitreal antibiotics injection. Cultures isolated Propionibacterium acnes. A retinal detachment was noted after 48 days, requiring a second pars plana vitrectomy and tamponade with sulfur hexafluoride gas. The retina remained attached. Visual acuity at 14 months follow-up was 20/200. Case 2: A 42-year-old male developed endophthalmitis two days after a penetrating injury of the right eye by a cat claw. Pars plana vitrectomy and intravitreal antibiotics injections were performed the same day. Cultures identified Pasteurella multocida. The patient progressed to panophthalmitis in 24 h and received intravenous antibiotics. He developed proliferative vitreoretinopathy with recurrent retinal detachments requiring multiple vitrectomies. His visual acuity was hand motions at 7 months follow-up. CONCLUSIONS AND RELEVANCE: Open globe injuries caused by cat claw may result in hyperacute and acute endophthalmitis. Propionibacterium acnes and Pasteurella multocida were isolated from the two cases reported here. Despite immediate interventions, both patients developed retinal detachment and had poor final visual acuity. Our report reveals that endophthalmitis caused by animal trauma is rare with potentially devastating outcomes, thereby requiring timely diagnosis and treatment.

Indexed as

Animal-related ocular traumaCat scratchEndophthalmitisOpen globe injury

Identifiers

PMID40327221
PMCPMC12055709

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.