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ArticleInternational journal of behavioral medicine2026

Harm Perception of Electronic Nicotine Delivery System Versus Regular Cigarettes in Singapore: Findings from a Nationwide Study.

Yen Sin Koh, Rajeswari Sambasivam, P V AshaRani, Edimansyah Abdin, Tan Chin Wee Bernard, Saleha Shafie, Stefan Ma, Wai Leng Chow, Siow Ann Chong, Yvette van der Eijk and 1 more

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Article in International journal of behavioral medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

11 authors.

Yen Sin KohInstitute of Mental Health, Singapore, Singapore. Yen_Sin_KOH@imh.com.sg.
Rajeswari SambasivamInstitute of Mental Health, Singapore, Singapore.
P V AshaRaniInstitute of Mental Health, Singapore, Singapore.
Edimansyah AbdinInstitute of Mental Health, Singapore, Singapore.
Tan Chin Wee BernardInstitute of Mental Health, Singapore, Singapore.
Saleha ShafieInstitute of Mental Health, Singapore, Singapore.
Stefan MaMinistry of Health, Singapore, Singapore.
Wai Leng ChowMinistry of Health, Singapore, Singapore.
Siow Ann ChongInstitute of Mental Health, Singapore, Singapore.
Yvette van der EijkNational University of Singapore, Singapore, Singapore.
Mythily SubramaniamInstitute of Mental Health, Singapore, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSingapore has strict regulations for electronic nicotine delivery system (ENDS). Hence, its residents may have different risk perceptions of ENDS compared to countries with more liberal measures. This study examined the prevalence of perceived risk of harm for ENDS versus cigarettes, their correlates, and the moderating effect of smoking status on significant associations in Singapore.

methodThis cross-sectional study utilized data from the Health and Lifestyle survey. The outcome was perceived risk of harm for ENDS versus regular cigarettes, categorized into "less harmful" and "about the same level of harm/more harmful." The correlates of interest were sociodemographic characteristics, depressive symptoms, anxiety symptoms, and smoking status. Correlates were examined using multivariable logistic regression. The moderating effect of smoking status was examined using interaction terms.

resultsA total of 6508 participants completed the question on perceived harm. Approximately 10.4% of them perceived ENDS to be less harmful than regular cigarettes. Moreover, 15.0% of never-smokers, 16.6% of former smokers, and 9.2% of ever-smokers reported that ENDS was less harmful than regular cigarettes. The following groups were more likely to perceive ENDS as less harmful than regular cigarettes: younger individuals, males, former smokers, current smokers, and those with higher depressive symptoms. Smoking status moderated the association between age group and perceived risk of harm.

conclusionThe harm perception of ENDS versus regular cigarettes is lower than in other countries. Future studies can examine the mediating role of harm perception of ENDS versus regular cigarettes on the association between depression and ENDS usage.

Indexed as

Cigarette SmokingElectronic Nicotine Delivery SystemsHealth Knowledge, Attitudes, PracticeTobacco ProductsAdultCross-Sectional StudiesDepressionFemaleHumansMaleMiddle AgedSingaporeYoung AdultCigarettesE-cigarettesENDSHarm perceptionSingaporeVaping

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.