ArticleAMB Express2025
Surface energetics of antibiofilm property of dental material added with green synthesized copper nanoparticles.
Article in AMB Express, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dental caries and lesions are difficult to treat during cement repairs. A remarkable antimicrobial therapeutic biomaterial is needed to fight dental caries and recurrent necrotic lesions. This study used Mentha longifolia extract to synthesize Copper nanoparticles (CuNPs) with distinctive properties at room temperature (22-25 °C). These CuNPs were supplemented with cephalosporin antibiotics that act as a capping agent to explore their synergistic antibacterial potency. These nanoparticles were subjected to FTIR, XRD, UV-Vis spectrophotometry, and SEM for characterisation. These CuNPs capped with antibiotics were added to glass ionomer (GIC) cement. These GIC samples were divided into pure GIC and modified GIC samples. Antibiotic-supplemented CuNPs, conjugated with GIC, showed good effect against Methicillin-resistant Staphylococcus aureus, Enterococcus faecalis, Klebsiella pneumoniae and Pseudomonas aeruginosa as compared to conventional GIC, tested through a modified direct contact test. Among them, GIC enriched with cefotaxime-supplemented CuNPs exhibited excellent antibacterial effects, followed by Cefepime and Ceftriaxone-supplemented CuNPs, respectively. Pure GIC has the most negligible antibacterial effect. Further, the interaction of these modified GICs with the selected bacterial strains was studied using the extended Derjaguin-Landau-Verwey-Overbeek (XDLVO) approach. The results show that the modified GIC effectively inhibited biofilm formation on dental implants.
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