Evidence map›Paper›PMID 40327105›Full record

ReviewRheumatology international2025

Successful infliximab therapy in systemic sarcoidosis presenting with giant leg ulcers: a case based review.

Nabil Belfeki, Nadia Ghariani Fetoui, Nour El Imene Ouni, Juliette Avci, Renaud Guedec-Ghelfi, Sonia Kammoun, Nouha Ghriss

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Rheumatology international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nabil BelfekiDepartment of Internal Medicine and Clinical Immunology, Groupe Hospitalier Sud-Ile de France, 270 Avenue Marc Jacquet, 77000, Melun, France. nabil.belfeki@ghsif.fr.
Nadia Ghariani FetouiDepartment of Dermatology, University Hospital Farhat Hached, Sousse, Tunisia.
Nour El Imene OuniDepartment of Dermatology, University Hospital Farhat Hached, Sousse, Tunisia.ORCID http://orcid.org/0000-0001-8052-8363
Juliette AvciDepartment of Internal Medicine and Clinical Immunology, University Hospital La Pitié Salpêtrière, Paris, France.
Renaud Guedec-GhelfiEVESIO Department of Nuclear Medicine, Melun, France.ORCID http://orcid.org/0009-0000-1292-9990
Sonia KammounDepartment of Internal Medicine and Clinical Immunology, Groupe Hospitalier Sud-Ile de France, 270 Avenue Marc Jacquet, 77000, Melun, France.
Nouha GhrissDepartment of Internal Medicine and Clinical Immunology, Groupe Hospitalier Sud-Ile de France, 270 Avenue Marc Jacquet, 77000, Melun, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sarcoidosis is a chronic granulomatous inflammatory disease that primarily affects the lungs and skin. Cutaneous involvement occurs in approximately 30% of cases. We report herewith a rare case of a 55-year-old man with chronic, non-healing bilateral leg ulcers, ultimately diagnosed as ulcerative cutaneous sarcoidosis through histopathological confirmation. Giant leg ulcers complicating systemic sarcoidosis is rare and its management is challenging because there are no specific recommendation. In our case, a 24-month course of intravenous infliximab associated with oral prednisone induced sustained clinical remission. The current decline is three years. The aim of our work is to review the clinical presentation and management of ulcerative cutaneous sarcoidosis and compare them to reported cases in literature.

Indexed as

InfliximabLeg UlcerSarcoidosisHumansMaleMiddle AgedPrednisoneTreatment OutcomeInfliximabPrednisoneInfliximabLeg ulcersNoncaseating granulomasOrgan involvementSarcoidosisSkin biopsy

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.