ReviewJournal of the American Academy of Orthopaedic Surgeons. Global research & reviews2025
Nontuberculosis Mycobacterium Infections in Orthopaedic Surgery: Review of the Epidemiology, Pathogenesis, Diagnosis, and Treatment Guidelines.
Review in Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Vertebral osteomyelitis caused by nontuberculous mycobacteria: a case series of 23 patients and a review of 108 cases in the literature.BMC infectious diseases · 2026Review
- Segmental instrumentation in spinal infections: evaluating the role of metal implants in treatment outcomes.Journal of medicine and life · 2026Article
- Extended Antibiotic Spacer use in an Infected Total Knee Arthroplasty with Mycobacterium intracellulare - A Case Report.Journal of orthopaedic case reports · 2026Article
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Authors and funding
3 authors.
Funding
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Abstract
Nontuberculosis Mycobacterium infections are rare but devastating infections in orthopaedic surgery. The complexity of treatment and the high rate of treatment failure for nontuberculosis Mycobacterium infections illustrate their unique pathogenesis and success at evading normal immune responses. To date, there is no formal treatment algorithm developed for managing these infections in orthopaedic surgery. Successful eradication relies on prolonged culture-specific antibiotic therapies coupled with surgical resection, implant/prosthesis removal, and occasionally amputations. These multidrug therapies often have a high rate of complications, drug-drug interactions, and poor tolerance, further increasing the complexity of treatment. Outlining the epidemiology, pathogenesis, diagnosis, and treatment guidelines of these rare but detrimental infections is essential to improving treatment success.
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