Evidence map›Paper›PMID 40326965›Full record

Trial reportJournal of the American Academy of Orthopaedic Surgeons. Global research & reviews2025

Limb Occlusion Pressure Versus Standard Pneumatic Tourniquet Pressure in Anterior Cruciate Ligament Surgery: A Randomized Controlled Trial.

Justin Aflatooni, Haley Goble, Bradley Lambert, Shari Liberman, Patrick C McCulloch

Abstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Justin AflatooniFrom the Houston Methodist Hospital, Houston Methodist Orthopedics and Sports Medicine, Houston, TX.
Haley Goble
Shari Liberman
Patrick C McCulloch

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTourniquets are frequently used to minimize blood loss. Standard pressures (STPs) are typically higher than minimum limb occlusion pressure (LOP), which can contribute to postoperative pain among other complications. We sought to investigate the effect of STP versus LOP on postoperative pain and opioid medication use after anterior cruciate ligament reconstruction (ACLR).

methodsSixty patients (age = 37 ± 15 years) undergoing ACLR were recruited and randomized into STP (275 mm Hg; M = 15/F = 15) or LOP (180 ± 29 mm Hg; M = 15/F = 15) group. A photoplethysmography probe was used to determine appropriate tourniquet pressures for the LOP group. Tourniquet and surgical site pain (Visual Analog Scale scores 0 to 10), as well as opioid medication usage, was recorded for 14 days after surgery. A generalized linear mixed model was used to detect differences in pain and medication use over the 14 days. The type-I error was defined as = 0.05.

resultsTourniquet site pain was less in the LOP group during postoperative days (PODs) 1 to 5 (P < 0.05) and averaged across the two-week postoperative period (P = 0.015). Surgery site pain was less in the LOP group at PODs 9 and 14 (P < 0.05). Reduced opioid medication use was observed in the LOP group at PODs 3, 4, and 7 and averaged across the postoperative window (P < 0.05).

conclusionIndividualized LOPs yield decreased postoperative pain and narcotic use compared with STP during ACLR.

Indexed as

Anterior Cruciate Ligament ReconstructionBlood Loss, SurgicalPostoperative PainPressureTourniquetsAdultAnalgesics, OpioidFemaleHumansMaleMiddle AgedPain MeasurementAnalgesics, Opioid

Identifiers

PMID40326965
PMCPMC12045532

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.