Evidence map›Paper›PMID 40326876›Full record

Observational studyRadiology2025

Maximum Resection of Noncontrast-enhanced Tumor at MRI Is a Favorable Prognostic Factor in IDH Wild-Type Glioblastoma.

Hye Hyeon Moon, Doonyaporn Wongsawaeng, Ji Eun Park, Seo Young Park, Seunghee Baek, Young-Hoon Kim, Sang Woo Song, Chang-Ki Hong, Jeong Hoon Kim, Myung Hwan Lee and 5 more

Abstract readObservational Study
In one paragraph

Observational study in Radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Hye Hyeon Moon *Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, 43 Olympic-ro 88, Songpa-Gu, Seoul 05505, Korea.ORCID 0000-0001-8484-3117
Doonyaporn Wongsawaeng *Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.ORCID 0000-0002-0418-5191
Ji Eun ParkDepartment of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, 43 Olympic-ro 88, Songpa-Gu, Seoul 05505, Korea.ORCID 0000-0002-4419-4682
Seo Young ParkDepartment of Statistics and Data Science, Korea National Open University, Seoul, Korea.ORCID 0000-0002-2702-1536
Seunghee BaekDepartment of Statistics and Epidemiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.ORCID 0000-0002-7063-969X
Young-Hoon KimDepartment of Neurosurgery, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.ORCID 0000-0002-8852-6503
Sang Woo SongDepartment of Neurosurgery, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.ORCID 0000-0002-5523-3798
Chang-Ki HongDepartment of Neurosurgery, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.ORCID 0000-0002-2761-0373
Jeong Hoon KimDepartment of Neurosurgery, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.ORCID 0000-0001-7385-2368
Myung Hwan LeeDepartment of Radiology and Research Institute of Radiological Science and Center for Clinical Imaging Data Science, Yonsei University College of Medicine, Seoul, South Korea.ORCID 0000-0002-7971-0624
Yae Won ParkDepartment of Radiology and Research Institute of Radiological Science and Center for Clinical Imaging Data Science, Yonsei University College of Medicine, Seoul, South Korea.ORCID 0000-0001-8907-5401
Sung Soo AhnDepartment of Radiology and Research Institute of Radiological Science and Center for Clinical Imaging Data Science, Yonsei University College of Medicine, Seoul, South Korea.ORCID 0000-0002-0503-5558
Jeffrey Michael PollockDepartment of Radiology, Oregon Health and Science University, Portland, Ore.ORCID 0000-0003-4317-779X
Ramon Francisco BarajasDepartment of Radiology, Oregon Health and Science University, Portland, Ore.ORCID 0000-0001-5093-4168
Ho Sung KimDepartment of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, 43 Olympic-ro 88, Songpa-Gu, Seoul 05505, Korea.ORCID 0000-0002-9477-7421

Funding

Leveraging Biologically Specific PET/MRI Monitoring and Therapeutic Modulation of the Hypoxic Glioblastoma Tumor Immune Microenvironment into Improved OutcomesR37CA288577 · NCI · OREGON HEALTH & SCIENCE UNIVERSITY · PI Ramon Francisco Barajas · 2024 to 2026
$1.6M
Defining the Hypoxic Immunosuppressive Microenvironment as a Biomarker of Therapy Efficacy in Glioblastoma Using Iron Oxide Enhanced FMISO PET/MRIK08CA237809 · NCI · OREGON HEALTH & SCIENCE UNIVERSITY · PI BARAJAS, RAMON FRANCISCO · 2020 to 2024
$1.2M
A multifunctional nanomaterial platform for reducing morbidity in medulloblastoma therapyR21NS135452 · NINDS · OREGON HEALTH & SCIENCE UNIVERSITY · PI BARAJAS, RAMON FRANCISCO, YILDIRIM, ADEM · 2024 to 2025
$426k
NCI NIH HHS K08 CA237809NCI NIH HHS L30 CA220897NCI NIH HHS R37 CA288577NINDS NIH HHS R21 NS135452
6 · The paper itself

Abstract

Background Isocitrate dehydrogenase (IDH) wild-type glioblastoma often includes a noncontrast-enhanced tumor (NET) component, and the extent of NET resection may serve as a prognostic marker. Purpose To assess clinical outcomes based on gross total resection (GTR) of NET, develop a real-world survival model incorporating GTR-NET for IDH wild-type glioblastoma, and validate the findings in multinational external cohorts. Materials and Methods A retrospective analysis included patients with IDH wild-type glioblastoma in a prospective registry (March 2017 to October 2020) as the training set. External validation used consecutive patients from two centers (March 2017 to January 2023). Patients were stratified into three groups: GTR-NET, GTR in contrast-enhanced tumor (CET) only, and no GTR. A conditional inference tree (CIT) model was developed using GTR type, age, and O

Indexed as

Brain NeoplasmsGlioblastomaMagnetic Resonance ImagingAdultAgedContrast MediaFemaleHumansIsocitrate DehydrogenaseMaleMiddle AgedPrognosisRetrospective StudiesContrast MediaIsocitrate Dehydrogenase

Identifiers

PMID40326876
PMCPMC12127958

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.