Evidence map›Paper›PMID 40326533›Full record

ArticleeLife2025

Differences in size and number of embryonic type II neuroblast lineages correlate with divergent timing of central complex development between beetle and fly.

Simon Rethemeier, Sonja Fritzsche, Dominik Mühlen, Gregor Bucher, Vera S Hunnekuhl

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Cambrian Artiopoda Reveals a Constraint in Euarthropod Brain Evolution.bioRxiv : the preprint server for biology · 2026
    Article
  2. Emerging tools to advance neuroethology in butterflies and moths.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2026
    Review
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  5. Review
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Simon RethemeierUniversity of Göttingen, Johann-Friedrich-Blumenbach Institute, GZMB, Department of Evolutionary Developmental Genetics, Göttingen, Germany.ORCID https://orcid.org/0009-0007-6990-7961
Sonja FritzscheUniversity of Göttingen, Johann-Friedrich-Blumenbach Institute, GZMB, Department of Evolutionary Developmental Genetics, Göttingen, Germany.ORCID https://orcid.org/0000-0003-3335-3534
Dominik MühlenUniversity of Göttingen, Johann-Friedrich-Blumenbach Institute, GZMB, Department of Evolutionary Developmental Genetics, Göttingen, Germany.ORCID https://orcid.org/0000-0002-0530-9360
Gregor BucherUniversity of Göttingen, Johann-Friedrich-Blumenbach Institute, GZMB, Department of Evolutionary Developmental Genetics, Göttingen, Germany.ORCID https://orcid.org/0000-0002-4615-6401
Vera S HunnekuhlUniversity of Göttingen, Johann-Friedrich-Blumenbach Institute, GZMB, Department of Evolutionary Developmental Genetics, Göttingen, Germany.ORCID https://orcid.org/0000-0002-9100-2161

Funding

Göttingen Promotionskolleg für Medizinstudierende Jacob-Henle-Programm
6 · The paper itself

Abstract

The insect brain and the timing of its development underwent evolutionary adaptations. However, little is known about the underlying developmental processes. The central complex of the brain is an excellent model to understand neural development and divergence. It is produced in large parts by type II neuroblasts, which produce intermediate progenitors, another type of cycling precursor, to increase their neural progeny. Type II neuroblasts lineages are believed to be conserved among insects, but little is known on their molecular characteristics in insects other than flies.

Indexed as

BrainCell LineageDrosophilaNeural Stem CellsTriboliumAnimalsGene Expression Regulation, Developmentalcentral complexdevelopmental biologyevolutionary biologyinsect brain developmentneuroblastsTribolium castaneum

Identifiers

PMID40326533
PMCPMC12055003

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.