Evidence map›Paper›PMID 40326461›Full record

ArticleBiometrics2025

Data integration methods for micro-randomized trials.

E Huch, I Nahum-Shani, L Potter, C Lam, D W Wetter, W Dempsey

Abstract read
In one paragraph

Article in Biometrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

E HuchDepartment of Statistics, University of Michigan, Ann Arbor, MI 48109, United States.ORCID 0000-0002-3822-1883
I Nahum-ShaniInstitute for Social Research, University of Michigan, Ann Arbor, MI 48104, United States.ORCID 0000-0001-6138-9089
L PotterDepartment of Population Health Sciences and Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84108, United States.ORCID 0000-0001-6681-8145
C LamDepartment of Population Health Sciences and Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84108, United States.
D W WetterDepartment of Population Health Sciences and Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84108, United States.
W DempseyInstitute for Social Research, University of Michigan, Ann Arbor, MI 48104, United States.

Funding

Pilot and Mentoring CoreP50DA054039 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LINDA M COLLINS, SUSAN A MURPHY · 2021 to 2026
$18.2M
Affective science and smoking cessation: Real time real world assessmentR01CA224537 · NCI · UNIVERSITY OF UTAH · PI LAM, CHO YAN · 2018 to 2023
$3.1M
Novel use of mHealth data to identify states of vulnerability and receptivity to JITAIs SupplementU01CA229437 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI NAHUM-SHANI, INBAL BILLIE, WETTER, DAVID W · 2018 to 2022
$2.8M
Leveraging ML algorithms and data integration techniques to improve efficiency of causal moderation analyses of micro-randomized trial dataR01GM152549 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Walter Dempsey · 2024 to 2026
$918k
Using mHealth to investigate intersectionality and health behaviors: Implications for conceptual models and cancer prevention interventions for marginalized populationsR00CA252604 · NCI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI POTTER, LINDSEY · 2023 to 2025
$747k
Huntsman Cancer Foundation P50DA054039NCI NIH HHS R01 CA224537NCI NIH HHS U01 CA229437NIDA NIH HHS P50 DA054039NIGMS NIH HHS R01 GM152549NIH/NCI R00CA252604NIH/NIDA R01GM152549NIH/NIGMS U01CA229437
6 · The paper itself

Abstract

Existing statistical methods for the analysis of micro-randomized trials (MRTs) are designed to estimate causal excursion effects using data from a single MRT. In practice, however, researchers can often find previous MRTs that employ similar interventions. In this paper, we develop data integration methods that capitalize on this additional information, leading to statistical efficiency gains. To further increase efficiency, we demonstrate how to combine these approaches according to a generalization of multivariate precision weighting that allows for correlation between estimates, and we show that the resulting meta-estimator possesses an asymptotic optimality property. We illustrate our methods in simulation and in a case study involving 2 MRTs in the area of smoking cessation, finding that the proposed methods can reduce standard errors by over 30% without sacrificing asymptotic unbiasedness or calibrated statistical inference.

Indexed as

BiometryModels, StatisticalRandomized Controlled Trials as TopicComputer SimulationData Interpretation, StatisticalHumansSmoking Cessationcausal excursion effectmeta-analysismicro-randomized trialmobile health

Identifiers

PMID40326461
PMCPMC12444755

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.