Evidence map›Paper›PMID 40326208›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2025

Solvent-Free Process for Preparing Metal-Organic Framework Composites Based on Carbon-Based Quantum Dots and Their Derivatives as Drug Delivery Systems for Andrographolide.

Wenndy Pantoja-Romero, Alexis Lavín-Flores, Gerardo Morell, Magaly Martínez-Ferrer, Brad R Weiner, Joaquín Coronas

Abstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wenndy Pantoja-RomeroDepartment of Chemistry, University of Puerto Rico at Rio Piedras Campus, 601 Av. Universidad, San Juan, San Juan, Puerto Rico.
Alexis Lavín-FloresDepartment of Chemistry, University of Puerto Rico at Rio Piedras Campus, 601 Av. Universidad, San Juan, San Juan, Puerto Rico.
Gerardo MorellMolecular Sciences Research Center, University of Puerto Rico at Rio Piedras Campus, 1390 C. Juan Ponce de León, San Juan, 00926, Puerto Rico.
Magaly Martínez-FerrerDivision of Cancer Clinical & Translational Research, University of Puerto Rico Comprehensive Cancer Center, San Juan, 00936, Puerto Rico.
Brad R WeinerDepartment of Chemistry, University of Puerto Rico at Rio Piedras Campus, 601 Av. Universidad, San Juan, San Juan, Puerto Rico.
Joaquín CoronasInstituto de Nanociencia y Materiales de Aragón (INMA), Universidad de Zaragoza-CSIC, Zaragoza, 50018, Spain.

Funding

UPR/MDACC Partnership for Excellence in Cancer Research(Parent Grant U54 CA096297)U54CA096297 · NCI · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI SHARON Hermes GIORDANO, REYNOLD Eugenio LOPEZ-ENRIQUEZ · 2002 to 2026
$36.9M
Aragón GovernmentNational Institutes of Health/National Cancer CEX2023-001286-SNational Institutes of Health/National Cancer PID2022-138582OB-I00National Institutes of Health/National Cancer T68-23RNCI NIH HHS U54 CA096297
6 · The paper itself

Abstract

Andrographolide (ADG) was conjugated with MIL-53(Al), ZIF-8, carbon-based quantum dots (CBQDs) and doped carbon-based quantum dots (D-CBQDs) using high-pressure (0.3 GPa) contact. This solvent-free approach is environmentally friendly, energy-efficient, and time-saving, resulting in ADG-MOFs-CBQDs/D-CBQDs with physical properties comparable to those produced by traditional liquid phase encapsulation. The resulting nanocomposites were characterized using SEM, XRD, TGA, FT-IR, and

Indexed as

CarbonDiterpenesDrug CarriersMetal-Organic FrameworksQuantum DotsCell Line, TumorCell SurvivalDrug Delivery SystemsHumansNanocompositesSolubilitySolventsandrographolideCarbonDiterpenesDrug CarriersMetal-Organic FrameworksSolventshigh‐pressure chemistrymetal‐organic frameworksorganic‐inorganic hybrid compositesquantum dots

Identifiers

PMID40326208
PMCPMC12172584

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.