Evidence map›Paper›PMID 40326032›Full record

ArticleCurrent pharmaceutical design2026

The Quantitative Analysis of Solid Dosage Forms of Itopride using Raman Spectroscopy.

Iqra Naheed, Maida Ehsan, Haq Nawaz, Muhammad Irfan Majeed, Abdulrahman Alshammari, Norah A Albekairi, Arslan Ali, Tehseen Ijaz, Ayesha Saif, Haseeb Akbar and 2 more

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Article in Current pharmaceutical design, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Iqra NaheedDepartment of Chemistry, University of Agriculture Faisalabad, Faisalabad, 38000, Pakistan.
Maida EhsanDepartment of Chemistry, University of Agriculture Faisalabad, Faisalabad, 38000, Pakistan.
Haq NawazDepartment of Chemistry, University of Agriculture Faisalabad, Faisalabad, 38000, Pakistan.
Muhammad Irfan MajeedDepartment of Chemistry, University of Agriculture Faisalabad, Faisalabad, 38000, Pakistan.
Abdulrahman AlshammariDepartment of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Post Box 2455, Riyadh, 11451, Saudi Arabia.
Norah A AlbekairiDepartment of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Post Box 2455, Riyadh, 11451, Saudi Arabia.
Arslan AliDepartment of Chemistry, University of Agriculture Faisalabad, Faisalabad, 38000, Pakistan.
Tehseen IjazDepartment of Chemistry, University of Agriculture Faisalabad, Faisalabad, 38000, Pakistan.
Ayesha SaifDepartment of Chemistry, University of Agriculture Faisalabad, Faisalabad, 38000, Pakistan.
Haseeb AkbarDepartment of Chemistry, University of Agriculture Faisalabad, Faisalabad, 38000, Pakistan.
Aleena AzizDepartment of Chemistry, University of Agriculture Faisalabad, Faisalabad, 38000, Pakistan.
Rida FatimaDepartment of Chemistry, University of Agriculture Faisalabad, Faisalabad, 38000, Pakistan.

Funding

King Saud University, Riyadh, Saudi Arabia RSP2025R491
6 · The paper itself

Abstract

objectiveThis study explores the application of Raman spectroscopy for identifying and quantifying itopride in solid dosage forms with varying concentrations of active ingredients and excipients. Raman spectroscopy provides a non-invasive, rapid, and accurate detection method that is ideal for pharmaceutical analysis.

methodsThe Raman spectral features of itopride in solid dosage forms were analyzed using Principal Component Analysis (PCA) and Partial Least Squares Regression Analysis (PLS-RA) as multivariate data analysis techniques.

resultsPCA effectively distinguished Raman spectral data of various itopride drug samples. PLS-RA facilitated quantitative analysis, yielding an R

conclusionThese findings demonstrated that the concentration of itopride in pharmaceutical samples using an established Partial Least Squares Regression calibration model can be determined with reliability.

Indexed as

BenzamidesBenzyl CompoundsSpectrum Analysis, RamanCalibrationDosage FormsLeast-Squares AnalysisPrincipal Component AnalysisBenzamidesBenzyl CompoundsDosage FormsitoprideItopridepartial least squares regression.principal component analysisquantitative analysisRaman spectroscopysolid dosage forms

Identifiers

PMID40326032

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.