Evidence map›Paper›PMID 40325912›Full record

ArticlePediatric pulmonology2025

Transcutaneous Carbon Dioxide Monitoring During Weaning From Mechanical Ventilation in Children: The WeanCO

Meryl Vedrenne-Cloquet, Charlotte Collignon, Noémie De Cacqueray, Mathilde Grapin, Mehdi Oualha, Sylvain Renolleau, Lucie Griffon, Sonia Khirani, Brigitte Fauroux

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In one paragraph

Article in Pediatric pulmonology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Meryl Vedrenne-CloquetPediatric Intensive Care Unit, AP-HP University Hospital Necker-Enfants malades, Paris, France.
Charlotte CollignonPediatric Intensive Care Unit, AP-HP University Hospital Necker-Enfants malades, Paris, France.ORCID http://orcid.org/0000-0002-2823-7080
Noémie De CacquerayPediatric Intensive Care Unit, AP-HP University Hospital Necker-Enfants malades, Paris, France.
Mathilde GrapinNephrology department, AP-HP University Hospital Necker-Enfants malades, Paris, France.
Mehdi OualhaPediatric Intensive Care Unit, AP-HP University Hospital Necker-Enfants malades, Paris, France.
Sylvain RenolleauPediatric Intensive Care Unit, AP-HP University Hospital Necker-Enfants malades, Paris, France.
Lucie GriffonPediatric Noninvasive Ventilation and Sleep Unit, EA 7330 VIFASOM, AP-HP University Hospital Necker-Enfants malades, Paris, France.
Sonia KhiraniPediatric Noninvasive Ventilation and Sleep Unit, EA 7330 VIFASOM, AP-HP University Hospital Necker-Enfants malades, Paris, France.ORCID http://orcid.org/0000-0003-4163-5021
Brigitte FaurouxPediatric Noninvasive Ventilation and Sleep Unit, EA 7330 VIFASOM, AP-HP University Hospital Necker-Enfants malades, Paris, France.ORCID http://orcid.org/0000-0001-6092-2662

Funding

The authors received no specific funding for this study.
6 · The paper itself

Abstract

introductionSpontaneous breathing trial (SBT) is recommended during weaning from mechanical ventilation (MV), but objective and easy tools lack to identify pediatric weaning failure. We aimed to assess whether changes in estimated arterial CO₂ (PaCO₂) derived from transcutaneous measurements (P

methodsChildren (age 72 h -18 years) with MV > 12 h were continuously monitored using a transcutaneous sensor to estimate PaCO₂ from skin CO₂ tension (P

resultsEighty children (median [IQR] age 1.1 [0.3; 8.7] years) were included, with 89 SBT (14 failures, 75 successes). Sixty-four patients were extubated following their first SBT, with 10 (16%) extubation failures. P

conclusionEarly post-extubation increase in estimated PaCO₂ was associated with extubation failure, whereas P

Indexed as

Blood Gas Monitoring, TranscutaneousCarbon DioxideVentilator WeaningAdolescentAirway ExtubationChildChild, PreschoolFemaleHumansInfantMalePositive-Pressure RespirationRetrospective StudiesCarbon Dioxidechildrenextubationmechanical ventilationspontaneous breathing trialtranscutaneous carbon dioxide

Identifiers

PMID40325912
PMCPMC12053114

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.