Evidence map›Paper›PMID 40325836›Full record

Trial reportBrain and behavior2025

Efficacy of Individual Placement and Support (IPS) on Employment, Education, and Training in Young Adults With Early Psychosis-A Randomized Controlled Trial.

Dorothea Jäckel, Andreas Bechdolf, Eva Burkhardt, Michèle Kallenbach, Marie-Luise Gamig, Anna Mößnang, Karolina Leopold

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Brain and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dorothea JäckelVivantes Klinikum Am Urban, Department of Psychiatry, Psychotherapy, and Psychosomatics Incorporating FRITZ at Urban and Soulspace, Vivantes Urban Hospital and Vivantes Friedrichshain Hospital, Berlin, Germany.ORCID https://orcid.org/0000-0003-0456-7840
Andreas BechdolfVivantes Klinikum Am Urban, Department of Psychiatry, Psychotherapy, and Psychosomatics Incorporating FRITZ at Urban and Soulspace, Vivantes Urban Hospital and Vivantes Friedrichshain Hospital, Berlin, Germany.
Eva BurkhardtUniversity Hospital for Child and Adolescent Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland.
Michèle KallenbachVivantes Klinikum Am Urban, Department of Psychiatry, Psychotherapy, and Psychosomatics Incorporating FRITZ at Urban and Soulspace, Vivantes Urban Hospital and Vivantes Friedrichshain Hospital, Berlin, Germany.
Marie-Luise GamigVivantes Klinikum Am Urban, Department of Psychiatry, Psychotherapy, and Psychosomatics Incorporating FRITZ at Urban and Soulspace, Vivantes Urban Hospital and Vivantes Friedrichshain Hospital, Berlin, Germany.
Anna MößnangVivantes Klinikum Am Urban, Department of Psychiatry, Psychotherapy, and Psychosomatics Incorporating FRITZ at Urban and Soulspace, Vivantes Urban Hospital and Vivantes Friedrichshain Hospital, Berlin, Germany.
Karolina LeopoldVivantes Klinikum Am Urban, Department of Psychiatry, Psychotherapy, and Psychosomatics Incorporating FRITZ at Urban and Soulspace, Vivantes Urban Hospital and Vivantes Friedrichshain Hospital, Berlin, Germany.

Funding

Otsuka PharmaceuticalOtsuka Pharmaceutical Europe Ltd. (OPEL) 17-029-stud
6 · The paper itself

Abstract

objectiveTo explore the efficiency of IPS on employment, education, and training (EET) outcomes in young adults with early psychosis.

methodsMonocenter parallel arm, randomized controlled trial.

interventionIndividual placement and support (IPS) according to the IPS-Y Fidelity Scale with an add-on of up to eight sessions of adherence therapy.

main outcome measuresEET at least 15 h per week for at least 1 week in the follow-up. Secondary outcomes included EET rates, duration in EET, and total wages. Additionally, subsample analyses were carried out.

resultsA total of 94 young adults (18-35 years) with early psychosis in an outpatient psychiatric service were randomly assigned to 12-month IPS according to program fidelity and standard care versus standard care alone. Four patients were excluded from the analysis because of early dropout after baseline, leaving 90 participants-46 in the IPS group and 44 in the TAU group-for intention to treat (ITT) analysis. EET rate for at least 15 h per week was significantly higher in the IPS group, 78% (36/46) versus 55% (24/44) in the TAU group. The percentage of participants in EET for at least 1 week in the follow-up was 83% (38/46) versus 59% (26/44). The number of weeks in EET was significantly higher in the IPS group (mean = 31.5 weeks, SD = 20.5 versus mean = 18.4 weeks, SD = 21.2), and the total wages were higher in favor of the IPS group (mean = €10,242, SD = 13,437 versus mean = €5217, SE = 7871).

conclusionIPS integrated into outpatient psychiatric services improves EET in young adults with early psychosis in Germany.

Indexed as

EmploymentEmployment, SupportedPsychotic DisordersAdolescentAdultFemaleHumansMaleTreatment OutcomeYoung Adultearly interventionearly psychosisfunctional recoveryNEETsupported educationsupported employmenttraining

Identifiers

PMID40325836
PMCPMC12053063

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.