Evidence map›Paper›PMID 40325535›Full record

ReviewCurrent topics in medicinal chemistry2025

Recent Synthetic Advancement and Medicinal Applications of Asymmetric Cyclic Pyrazoline-based Hydrazine Derivatives: A Review.

Dattatraya Raut, Dnyandev Bhosale, Raghunath Bhosale, Anjana Lawand, Mahesh Hublikar

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current topics in medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dattatraya RautVishwasrao Naik Arts, Commerce, and Baba Naik Science Mahavidyalaya, Shirala District- Sangli, Maharashtra State, 415408, India.ORCID 0000-0003-2684-3383
Dnyandev BhosaleDepartment of Chemistry Pratapsinh Mohite-Patil Mahavidyalaya, Karmala District-Solapur, Maharashtra State, 413203, India.
Raghunath BhosaleSchool of Chemical Sciences, Punyashlok Ahilyadevi Holkar Solapur University, Solapur, Maharashtra State, 413255, India.
Anjana LawandSchool of Chemical Sciences, Punyashlok Ahilyadevi Holkar Solapur University, Solapur, Maharashtra State, 413255, India.
Mahesh HublikarSchool of Chemical Sciences, Punyashlok Ahilyadevi Holkar Solapur University, Solapur, Maharashtra State, 413255, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemistry research focuses on reducing energy and minimizing harmful byproducts. Pyrazoline and its derivatives have various pharmacological properties. This study aims to compile procedures for creating pyrazoline scaffolds from academic articles and online resources, such as Scopus, Google Scholar, Web of Science, Science Direct, Research Gate and libraries, aiming to minimize environmental and human health impacts. The primary objective is to determine the structural modifications and chemical groups that enhance their bioactivity, low toxicity, and handling. Furthermore, the review explores the bioavailability, synthetic challenges, and progress made in utilising pyrazoline derivatives in pharmaceutical and synthetic organic chemistry. The only goal is to provide insight into the creation of pyrazoline hybrid molecules that are very effective and less hazardous.

Indexed as

HydrazinesPyrazolesHumansMolecular StructureHydrazinesPyrazolesAsymmetric cyclic hydrazinemedicinal applicationspyrazoline-based hydrazine derivatives.syntheses methods

Identifiers

PMID40325535

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.