Evidence map›Paper›PMID 40325531›Full record

ArticleCurrent medical imaging2025

A Contrast-enhanced Ultrasound Grading of Lymphatic Vessels: A Correlative Study and A Therapeutic Suggestion to Secondary Limb Lymphoedema

Ping Fu, Jia Zhu, Zijie Liu, Shentao Zhang, Shahi Kishor, Li Chen, Zhengren Liu, Lili Zhang

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Article in Current medical imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Ping FuDepartment of Ultrasound, The 1st Affiliated Hospital, Jiangxi Medical College, Nanchang University, No.17 Yong Wai Zheng Street, Nanchang, 330006, China.
Jia ZhuDepartment of General Surgery, The 1st Affiliated Hospital, Jiangxi Medical College, Nanchang University, No.17 Yong Wai Zheng Street, Nanchang, 330006, China.
Zijie LiuDepartment of Ultrasound, The 1st Affiliated Hospital, Jiangxi Medical College, Nanchang University, No.17 Yong Wai Zheng Street, Nanchang, 330006, China.
Shentao ZhangDepartment of Ultrasound, The 1st Affiliated Hospital, Jiangxi Medical College, Nanchang University, No.17 Yong Wai Zheng Street, Nanchang, 330006, China.
Shahi KishorDepartment of Endocrinology and Metabolism, The 1st Affiliated Hospital, Jiangxi Medical College, Nanchang University,No.17 Yong Wai Zheng Street, Nanchang, 330006, China.
Li ChenDepartment of Ultrasound, The 1st Affiliated Hospital, Jiangxi Medical College, Nanchang University, No.17 Yong Wai Zheng Street, Nanchang, 330006, China.
Zhengren LiuDepartment of General Surgery, The 1st Affiliated Hospital, Jiangxi Medical College, Nanchang University, No.17 Yong Wai Zheng Street, Nanchang, 330006, China.
Lili ZhangDepartment of Ultrasound, The 1st Affiliated Hospital, Jiangxi Medical College, Nanchang University, No.17 Yong Wai Zheng Street, Nanchang, 330006, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVarious methods have been employed to evaluate secondary limb lymphedema, each with its own set of limitations.

objectivesTo delve into a novel approach to lymphatic grading, specifically utilizing enhanced ultrasound for assessing lymphatic function, to compensate for the shortcomings of other methods to some extent. MATERIALS AND

methodsThe clinical and ultrasound data of 51 patients with secondary limb lymphedema from June 2022 to September 2023 were retrospectively analyzed. The characteristic ultrasound manifestations of all visualized lymphatic vessels were studied. A contrast-enhanced ultrasound grading of lymphatic vessels (Ceus-Clv) was formulated and applied to grade the 51 patients. The study also correlated Ceus-Clv with Campisi clinical stage, postoperative duration, and duration of edema.

resultsOut of 51 patients, there were 19 cases of Ceus-Clv I, 10 cases of Ceus-Clv II, 19 cases of Ceus-Clv III, and 3 cases of Ceus-Clv IV. The correlation coefficient (rs) between Ceus-Clv and Campisi clinical stages was 0.958 (P < 0.001). Similarly, the correlation coefficient between Ceus-Clv and postoperative duration was 0.824 (P < 0.001), and between Ceus-Clv and duration of edema was 0.763 (P < 0.001).

conclusionCeus-Clv grading is a safe, convenient, and effective method for assessing lymphatic vessel function in secondary limb edema. This method can accurately reflect the patient's lymphatic vessel function and the severity of edema, providing valuable guidance for the treatment of secondary limb edema.

Indexed as

Contrast MediaLymphatic VesselsLymphedemaAdolescentAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesUltrasonographyYoung AdultContrast MediaContrast-enhanced ultrasound grading of lymphatic vessels.Function of lymphatic vesselsPostoperative tumorSecondary limb lymphoedema

Identifiers

PMID40325531
PMCPMC13181199

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