Evidence map›Paper›PMID 40325392›Full record

ArticleEuropean journal of medical research2025

Aminooxyacetic acid ameliorates alcohol-induced learning and memory deficits through BDNF-TrkB pathway and calcium homeostasis.

Zhen Sun, Meinan Nie, Xunling Wang, Bolin Jiao, Jiayi Fu, Ailin Du

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhen Sun *Sino-UK International Joint Laboratory of Brain Injury in Henan Province, Henan International Joint Laboratory of Neuromodulation, Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xinxiang Medical University, No. 601, Jinsui Road, Xinxiang, China.
Meinan Nie *Sino-UK International Joint Laboratory of Brain Injury in Henan Province, Henan International Joint Laboratory of Neuromodulation, Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xinxiang Medical University, No. 601, Jinsui Road, Xinxiang, China.
Xunling Wang *Sino-UK International Joint Laboratory of Brain Injury in Henan Province, Henan International Joint Laboratory of Neuromodulation, Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xinxiang Medical University, No. 601, Jinsui Road, Xinxiang, China.
Bolin JiaoSino-UK International Joint Laboratory of Brain Injury in Henan Province, Henan International Joint Laboratory of Neuromodulation, Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xinxiang Medical University, No. 601, Jinsui Road, Xinxiang, China.
Jiayi FuSino-UK International Joint Laboratory of Brain Injury in Henan Province, Henan International Joint Laboratory of Neuromodulation, Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xinxiang Medical University, No. 601, Jinsui Road, Xinxiang, China.
Ailin DuSino-UK International Joint Laboratory of Brain Injury in Henan Province, Henan International Joint Laboratory of Neuromodulation, Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xinxiang Medical University, No. 601, Jinsui Road, Xinxiang, China. duailin@126.com.

Funding

Doctoral Research Initiation Project of Xinxiang Medical University 505367Henan Province Key Scientific Research Projects of Higher Education Institutions 15A310006
6 · The paper itself

Abstract

Chronic alcohol-related brain damage (ARBD) is mainly manifested as learning and memory impairment and cognitive decline in the long term. Ca

Indexed as

AlcoholismAminooxyacetic AcidBrain-Derived Neurotrophic FactorCalciumMembrane GlycoproteinsMemory DisordersReceptor, trkBAnimalsCell Line, TumorEthanolHomeostasisHumansMaleMaze LearningMitochondriaRatsAminooxyacetic AcidBdnf protein, ratBrain-Derived Neurotrophic FactorCalciumEthanolMembrane GlycoproteinsNtrk2 protein, ratReceptor, trkBAOAABDNF-TrkB pathwayBIPCBSChronic alcoholismEndoplasmic reticulum stressH2SLearning and memoryMitochondrial damage

Identifiers

PMID40325392
PMCPMC12054319

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.