ArticleBMC cardiovascular disorders2025
Triglyceride-glucose index: a novel predictor of major adverse cardiovascular events and cerebrovascular events in patients with acute ST-segment elevation myocardial infarction.
Article in BMC cardiovascular disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- The impact of triglyceride-glucose index on short-term prognosis in patients with acute myocarditis.BMC cardiovascular disorders · 2026Article
- Association of Triglyceride-Glucose Index with Angiographic Thrombus Burden in Patients with ST-Elevation Myocardial Infarction: A Prospective Observational Study.Journal of clinical medicine · 2026Article
- Prognostic value of CTI for major adverse cardiovascular events in patients With ST-elevation myocardial infarction after primary percutaneous coronary intervention.Frontiers in cardiovascular medicine · 2026Article
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7 authors.
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Abstract
introductionNumerous studies have indicated the association of the triglyceride-glucose index (TyG) index with coronary artery disease, particularly myocardial infarction. However, limited mention exists regarding the predictive effects of major adverse cardiovascular events (MACE) and major adverse cardiac and cerebrovascular events (MACCE) in patients with ST-segment Elevation Myocardial Infarction (STEMI). This study aimed to investigate the predictive role of the TyG index on MACE and MACCE within 30 days in patients with STEMI.
methodsThis study enrolled 586 patients with STEMI and conducted lipid, glucose, and myocardial biochemical testing. The TyG index was calculated; univariate analysis, multivariate analysis, and logistic regression analysis were employed to further investigate the correlation of the TyG index with MACE and MACCE. Subsequently, restricted cubic spline (RCS) analysis was conducted to determine whether they exhibit a linear correlation.
resultsThe study reported 105 MACCE patients. The results revealed a significant positive correlation between the TyG index and the occurrence of MACE and MACCE (odds ratio [OR] = 1.461, 95% confidence interval [CI] [1.091-1.956], p = 0.011 and OR = 1.427, 95%CI [1.064-1.914], p = 0.017, respectively). In univariate and multivariate analysis, the TyG index remains correlated with MACE and MACCE even after adjusting for related variables. Subsequent RCS analysis, accounting for different factors such as age, white blood cell count, and N-terminal pro-B-type natriuretic peptide (NT-proBNP), indicated that the correlation of TyG index with MACE and MACCE remains linear (p-non-linear = 0.662, p-non-linear = 0.781, respectively).
conclusionThe TyG index effectively predicts MACE and MACCE in patients with STEMI within 30 days. CLINICAL TRIAL NUMBER: Not applicable.
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