Evidence map›Paper›PMID 40325365›Full record

Trial reportBMC pregnancy and childbirth2025

The value of subcutaneous tissue closure and drain in obese women undergo elective caesarean section: a randomized controlled trial.

Mohamed A Shalaby, Hanan H M Metwally, Ahmed M Maged, Yomna A Bayoumi, Noha Salah

Retracted Registry-linked trialAbstract readRandomized Controlled TrialRetracted Publication
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. It is linked to trial NCT04177381 (Comparative Study Between Subcutaneous Tissue Closure Versus Drain in Obese Women Undergo Elective Cesarean Section Arandomized Controlled Trial), which is not on this map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04177381 nacompletednot on this map

Comparative Study Between Subcutaneous Tissue Closure Versus Drain in Obese Women Undergo Elective Cesarean Section Arandomized Controlled Trial

TypeinterventionalSponsorCairo UniversityRan2021 to 2022Enrolled352ConditionsWound InfectionArmsCesarean section, subcutanous sutures, subcutanous drain
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Mohamed A ShalabyDepartment of Obstetrics and Gynecology, Kasr Al-Ainy Hospital, Cairo University, Cairo, Egypt. Mohamed_shalaby85@hotmail.com.
Hanan H M MetwallyDepartment of Obstetrics and Gynecology, Temi Elamdid Hospital, Mansoura, Dakahlia, Egypt.
Ahmed M MagedDepartment of Obstetrics and Gynecology, Kasr Al-Ainy Hospital, Cairo University, Cairo, Egypt.
Yomna A BayoumiDepartment of Obstetrics and Gynecology, Kasr Al-Ainy Hospital, Cairo University, Cairo, Egypt.
Noha SalahDepartment of Obstetrics and Gynecology, Kasr Al-Ainy Hospital, Cairo University, Cairo, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveto compare the efficacy and safety of subcutaneous suture reapproximation alone versus suture plus subcutaneous drain or non-closure for the prevention of wound complications in obese women undergoing elective cesarean delivery (CD).

methodsThis randomized controlled open label trial was conducted on 352 obese women candidates for elective CD. Participants were randomized into 4 groups: group I (n = 89) were allocated for interrupted closure of subcutaneous tissue with insertion of subrectus drain, group II (n = 88) were allocated for interrupted closure of subcutaneous tissue, group III (n = 88) were allocated for insertion of subrectus drain, group IV (n = 87) were allocated for non-closure of subcutaneous tissue without insertion of subrectus drain The primary outcome parameter was the development of wound complications including seroma, infection and dehiscence. Secondary outcome included postoperative pain assessed by VAS, postoperative fever, time of hospital stay and duration of surgery.

resultsThere were significant differences between the 4 groups regarding the mean duration of surgery (48.67 ± 2.84, 46.56 ± 4.80, 45.95 ± 4.29, and 41.59 ± 5.08 in combined, sutures only, drain only and none groups, respectively, P < 0.001). Assessment of outcome parameters revealed significant differences between the 4 groups regarding postoperative pain (2.93 ± 1.95, 3.62 ± 2.26, 3.83 ± 2.16, and 3.99 ± 2.032, P = 0.006), postoperative fever (3/68 (3.5%),5/86 (5.8%),3/68 (3.5%),, and 12/86 (14%), P = 0.017) wound infection (4/68 (4.7%),7/86 (8.1%),4/68 (4.7%),, and 13/86 (15.1%), P = 0.035) and wound dehiscence (4/68 (4.7%),6/86 (7%),8/68 (9.3%),, and 16/86 (18.6%), P = 0.011) and highly statistical significant differences regarding wound seroma (4/68 (4.7%),13/86 (15.1%),6/68 (7%),, and 21/86 (24.4%), P < 0.001) and redressing(10/68 (11.6%),17/86 (19.8%),19/68 (22.1%), and 32/86 (37.2%), P < 0.001) 08 in combined, sutures only, drain only and none groups, respectively.

conclusionThe additional use of a subcutaneous drain along with a standard subcutaneous suture reapproximation technique is effective for the prevention of wound complications named seroma, redressing, dehiscence and infection in obese women undergoing CD.

trial registrationNCT04177381 Date of registration: 21/11/2019.

Indexed as

Cesarean SectionDrainageObesitySubcutaneous TissueSuture TechniquesAdultElective Surgical ProceduresFemaleHumansLength of StayOperative TimePostoperative ComplicationsPostoperative PainPregnancySeromaSurgical Wound DehiscenceCaesarean sectionObeseSubcutaneous drainsSubcutaneous sutures, wound complicationsSurgical site infection

Identifiers

PMID40325365
PMCPMC12054301

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.