Evidence map›Paper›PMID 40325305›Full record

ArticleJournal of cancer survivorship : research and practice2025

Specification of self-reported late-term impairments 3-7 years after primary breast cancer treatment: a nationwide cross-sectional study among Danish breast cancer survivors.

Kim Michéle Feder, Kim Gordon Ingwersen, Hans Bjarke Rahr, Heidi Klakk Egebæk, Lonny Stokholm, Marianne Djernes Lautrup

Abstract read
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In one paragraph

Article in Journal of cancer survivorship : research and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Association Between Danish Guideline Treatments for Breast Cancer and Physiotherapy-Relevant Late Effects: A Nationwide Cohort Study.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kim Michéle FederDepartment of Physiotherapy, Vejle Hospital, University Hospital of Southern Denmark, Beriderbakken 4, 7100, Vejle, Denmark. kim.michele.feder@rsyd.dk.ORCID http://orcid.org/0000-0003-3088-1833
Kim Gordon IngwersenDepartment of Physiotherapy, Vejle Hospital, University Hospital of Southern Denmark, Beriderbakken 4, 7100, Vejle, Denmark.ORCID http://orcid.org/0000-0001-6800-4532
Hans Bjarke RahrDepartment of Regional Health Research, University of Southern Denmark, Campusvej 55, 5230, Odense, Denmark.ORCID http://orcid.org/0000-0002-4571-7852
Heidi Klakk EgebækDepartment for Applied Research and Development, University College South Denmark (UC SYD), Degnevej 16, 6705, Esbjerg, Denmark.ORCID http://orcid.org/0000-0002-9299-4334
Lonny StokholmOPEN, Open Patient data Explorative Network, J.B. Winsløws Vej 21, 3 Floor, 5000, Odense, Denmark.ORCID http://orcid.org/0000-0002-9727-6649
Marianne Djernes LautrupDepartment of Surgery, Vejle Hospital, University Hospital of Southern Denmark, Beriderbakken 4, 7100, Vejle, Denmark.ORCID http://orcid.org/0000-0002-6468-235X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo describe the characteristics of Danish women treated for primary breast cancer, the prevalence and severity of self-reported late-term impairments, and the registration of these impairments in the Danish National Patient Registry.

methodsThis is a nationwide cross-sectional survey study. A nationwide sample of 9927 women were invited to complete a questionnaire on late-term impairments, including shoulder impairment, lymphedema, fatigue, and chemotherapy-induced neuropathy. Severity was scored on validated patient-reported scales. Clinical characteristics of women and diagnostic codes for "late-term effects" were extracted from the Danish National Patient Registry.

resultsThe response rate was 60.9%. The 6046 responders were on average 57 years old at surgery, and 53.5% had a lower education level, 62.7% were married, 56.7% had a body mass index ≥ 25, and 54.4% had one or more co-morbidities. Overall, 60.7% reported having late-term impairments from their breast cancer treatment. The most common impairments were shoulder impairment (75.3%), fatigue (56.9%), chemotherapy-induced neuropathy (49.6%), and lymphedema (26.3%). On average, 58.0% women reporting impairments scored moderate to severe disturbances on validated patient-reported scales. Despite the high self-reported rates, impairments were rarely recorded in the Danish National Patient Registry (lymphedema, 1.3%; fatigue, 0.2%; shoulder impairment, 0.1%; and chemotherapy-induced neuropathy, 0.1%).

conclusionMore than 60% of Danish breast cancer survivors reported moderate to severe late-term impairments 3-7 years post-treatment, yet these impairments were rarely recorded in the Danish National Patient Registry. IMPLICATIONS FOR CANCER SURVIVORS: Future research should focus on organizational structures in the Danish secondary healthcare, in relation to facilitating screening and timely detection of late-term impairments.

Indexed as

Danish breast cancer survivorsNationwide questionnaireRegistry extractSelf-reported late-term impairmentsThe Danish secondary healthcare

Identifiers

PMID40325305

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.