Evidence map›Paper›PMID 40325299›Full record

ArticleJournal of pharmacokinetics and pharmacodynamics2025

Informatics for toxicokinetics.

Gilberto Padilla Mercado, Christopher Cook, Norman Adkins, Lucas Albrecht, Grace Cary, Brenda Edwards, Derik E Haggard, Nancy M Hanley, Michael F Hughes, Anna Jarnagin and 18 more

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of pharmacokinetics and pharmacodynamics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Gilberto Padilla MercadoCenter for Computational Toxicology and Exposure, Office of Research and Development, United States Environmental Protection Agency, Durham, NC, 27709, USA.ORCID 0000-0001-5423-1646
Christopher CookCenter for Computational Toxicology and Exposure, Office of Research and Development, United States Environmental Protection Agency, Durham, NC, 27709, USA.
Norman AdkinsCenter for Computational Toxicology and Exposure, Office of Research and Development, United States Environmental Protection Agency, Durham, NC, 27709, USA.
Lucas AlbrechtCenter for Computational Toxicology and Exposure, Office of Research and Development, United States Environmental Protection Agency, Durham, NC, 27709, USA.
Grace CaryCenter for Computational Toxicology and Exposure, Office of Research and Development, United States Environmental Protection Agency, Durham, NC, 27709, USA.
Brenda EdwardsCenter for Computational Toxicology and Exposure, Office of Research and Development, United States Environmental Protection Agency, Durham, NC, 27709, USA.
Derik E HaggardCenter for Computational Toxicology and Exposure, Office of Research and Development, United States Environmental Protection Agency, Durham, NC, 27709, USA.ORCID 0000-0001-5755-6761
Nancy M HanleyCenter for Computational Toxicology and Exposure, Office of Research and Development, United States Environmental Protection Agency, Durham, NC, 27709, USA.
Michael F HughesCenter for Computational Toxicology and Exposure, Office of Research and Development, United States Environmental Protection Agency, Durham, NC, 27709, USA.ORCID 0000-0002-5571-5447
Anna JarnaginCenter for Computational Toxicology and Exposure, Office of Research and Development, United States Environmental Protection Agency, Durham, NC, 27709, USA.
Tirumala D KodavantiCenter for Computational Toxicology and Exposure, Office of Research and Development, United States Environmental Protection Agency, Durham, NC, 27709, USA.
Evgenia Korol-BexellCenter for Computational Toxicology and Exposure, Office of Research and Development, United States Environmental Protection Agency, Durham, NC, 27709, USA.
Anna KreutzCenter for Computational Toxicology and Exposure, Office of Research and Development, United States Environmental Protection Agency, Durham, NC, 27709, USA.
Mayla NgoCenter for Computational Toxicology and Exposure, Office of Research and Development, United States Environmental Protection Agency, Durham, NC, 27709, USA.
Caitlyn PatulloCenter for Computational Toxicology and Exposure, Office of Research and Development, United States Environmental Protection Agency, Durham, NC, 27709, USA.
Evelyn G RowanCenter for Computational Toxicology and Exposure, Office of Research and Development, United States Environmental Protection Agency, Durham, NC, 27709, USA.ORCID 0000-0002-1200-6413
L McKenna HuseCenter for Computational Toxicology and Exposure, Office of Research and Development, United States Environmental Protection Agency, Durham, NC, 27709, USA.ORCID 0000-0001-5103-6116
Veronica A CorreaCenter for Computational Toxicology and Exposure, Office of Research and Development, United States Environmental Protection Agency, Durham, NC, 27709, USA.
Branislav KesicCenter for Computational Toxicology and Exposure, Office of Research and Development, United States Environmental Protection Agency, Durham, NC, 27709, USA.
Will CaseyCenter for Computational Toxicology and Exposure, Office of Research and Development, United States Environmental Protection Agency, Durham, NC, 27709, USA.
Jennat AboabdoCenter for Computational Toxicology and Exposure, Office of Research and Development, United States Environmental Protection Agency, Durham, NC, 27709, USA.ORCID 0009-0009-5461-8707
Kaitlyn WolfCenter for Computational Toxicology and Exposure, Office of Research and Development, United States Environmental Protection Agency, Durham, NC, 27709, USA.
Risa SayreCenter for Computational Toxicology and Exposure, Office of Research and Development, United States Environmental Protection Agency, Durham, NC, 27709, USA.ORCID 0000-0002-6173-8020
Bhaskar SharmaCenter for Computational Toxicology and Exposure, Office of Research and Development, United States Environmental Protection Agency, Durham, NC, 27709, USA.
Jonathan T WallCenter for Computational Toxicology and Exposure, Office of Research and Development, United States Environmental Protection Agency, Durham, NC, 27709, USA.ORCID 0000-0002-4610-8645
Hiroshi YamazakiShowa Pharmaceutical University, Machida, Tokyo, 194-8543, Japan.ORCID 0000-0002-1068-4261
John F WambaughCenter for Computational Toxicology and Exposure, Office of Research and Development, United States Environmental Protection Agency, Durham, NC, 27709, USA.ORCID 0000-0002-4024-534X
Caroline L RingCenter for Computational Toxicology and Exposure, Office of Research and Development, United States Environmental Protection Agency, Durham, NC, 27709, USA. ring.caroline@epa.gov.ORCID 0000-0002-0463-1251

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Toxicokinetic and pharmacokinetic (PK) summary parameters, such as C

Indexed as

ToxicokineticsAnimalsArea Under CurveDatabases, FactualHalf-LifeHumansModels, BiologicalPharmaceutical PreparationsPharmacokineticsUnited StatesUnited States Environmental Protection AgencyPharmaceutical PreparationsCurve fittingInformaticsOpen-source softwarePharmacokineticsToxicokinetics

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.