ReviewRadiologie (Heidelberg, Germany)2025
[Malignant non-Hodgkin's lymphoma : Current classification and biopsy diagnostics].
Review in Radiologie (Heidelberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
clinical/methodological issueImaging plays a central role in the staging and biopsy-based diagnosis of malignant lymphomas. The diagnostic approach using core needle biopsy requires an interdisciplinary strategy that integrates clinical, histopathological and molecular characteristics of non-Hodgkin's lymphomas (NHL). STANDARD RADIOLOGICAL
methodsUltrasound and/or computed tomography (CT)-guided biopsy. METHODOLOGICAL INNOVATIONS: The current WHO classification defines over 40 non-Hodgkin's lymphoma entities, taking the genomic heterogeneity into account. PERFORMANCE/ACHIEVEMENTS: This review focuses on non-Hodgkin's lymphomas with imaging-based diagnostic relevance, including indolent and aggressive B‑NHL as well as systemic T/NK-NHL. It also discusses technical aspects of core needle biopsy and treatment-related effects that can impact the biopsy quality. Special attention is paid to the role of imaging and biopsy techniques in detecting high-grade transformation of indolent B‑NHL, which is associated with rapid progression and diagnostic challenges. PRACTICAL RECOMMENDATIONS: Ultrasound-guided and CT-guided core needle biopsies are well-established standard procedures with a high sensitivity. Close interdisciplinary collaboration between radiology and pathology, along with structured communication of clinical information are essential to ensure high diagnostic accuracy.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.