Nonsurgical Temple Volumization with Soft-Tissue Fillers: A Systematic Review of the Literature.

backgroundFacial aging leads to cosmetically unappealing volume loss in the temples. We systematically reviewed the available literature regarding nonsurgical temporal volumization with injectable fillers.

methodsOn Sept 16, 2024, Medline, Scopus, Embase, and Cochrane databases were queried with relevant terms for all articles describing temporal volumization with injectable fillers, including those with temple-specific data within the context of full-face volumization. Studies unrelated to temporal volumization, using autologous fat or its derivatives, limited to temporal lifting via injection into the temporoparietal scalp, without novel clinical/patient data, or unavailable in English were excluded.

resultsDatabase query yielded 680 unique articles. One additional article was found with citation searching. After screening and evaluation for duplicates and inclusion/exclusion criteria, 40 articles were included. Nineteen studies were prospective and 21 studies were retrospective, of which 9 were complication case reports. A total of 881 patients were treated with either hyaluronic acid (n = 783), calcium hydroxylapatite (n = 93), polymethylmethacrylate (n = 28), allograft adipose matrix (n = 10), and poly-L-lactic acid (n = 2). Pooled data demonstrated improvement in temporal hollowing and global aesthetic improvement scales, as well as subject satisfaction. Pain/tenderness/pressure (29.6%), ecchymosis (17.3%), and edema (15.5%) were the most common posttreatment adverse events. Vascular events and other serious adverse events were rare. Deeper (supraperiosteal or inter/intra-fascial) injection may be more commonly associated with masticatory pain/discomfort.

conclusionsTemporal volume loss is a natural consequence of aging that can be safely and effectively improved with soft-tissue fillers. LEVEL OF EVIDENCE III: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .