Evidence map›Paper›PMID 40325042›Full record

ArticleScientific reports2025

Comparative transcriptome analysis of midgut of Bombyx mori under a sucrose-supplemented diet.

Zhenbin Hu, Lijie Zhan, Xinyi Chen, Jia Li, Meirong Zhang, Pingzhen Xu

Abstract readComparative Study
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhenbin Hu *Jiangsu Key Laboratory of Sericultural and Animal Biotechnology, School of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, 212100, Jiangsu, China.
Lijie Zhan *Jiangsu Key Laboratory of Sericultural and Animal Biotechnology, School of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, 212100, Jiangsu, China.
Xinyi ChenJiangsu Key Laboratory of Sericultural and Animal Biotechnology, School of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, 212100, Jiangsu, China.
Jia LiJiangsu Key Laboratory of Sericultural and Animal Biotechnology, School of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, 212100, Jiangsu, China.
Meirong ZhangJiangsu Key Laboratory of Sericultural and Animal Biotechnology, School of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, 212100, Jiangsu, China.
Pingzhen XuJiangsu Key Laboratory of Sericultural and Animal Biotechnology, School of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, 212100, Jiangsu, China. xpz198249@just.edu.cn.

Funding

Postgraduate Research & Practice Innovation Program of Jiangsu Province SJCX24_2568Postgraduate Research & Practice Innovation Program of Jiangsu Province SJCX24_2586
6 · The paper itself

Abstract

As a monophagous insect, the silkworm possesses a restricted feeding capacity. To investigate the impact of varying sucrose concentrations on silkworm growth and development, transcriptomic analyses were conducted on the silkworm midgut. A total of 909 differentially expressed genes (DEGs) were identified, with down-regulated genes predominantly associated with starch and sucrose metabolism, fructose and mannose metabolism, galactose metabolism, and amino sugar and nucleotide sugar metabolism. These alterations suggest that excessive sucrose consumption may suppress the carbohydrate metabolism pathway in silkworm. This study offers a comprehensive analysis of transcriptomic studies on high sucrose intake in silkworm, providing insights into the effects of varying sucrose concentrations on these organisms.

Indexed as

BombyxSucroseTranscriptomeAnimalsCarbohydrate MetabolismDietDietary SupplementsGene Expression ProfilingSucroseMetabolismMidgutSilkwormSucroseTranscriptome

Identifiers

PMID40325042
PMCPMC12053618

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.