ArticleNPJ Parkinson's disease2025
Will adaptive deep brain stimulation for Parkinson's disease become a real option soon? A Delphi consensus study.
Article in NPJ Parkinson's disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- The Place of Adaptive Deep Brain Stimulation in Parkinson's Disease: Spatial before Temporal Optimization.Movement disorders : official journal of the Movement Disorder Society · 2026Article
- Activity-dependent adaptive deep brain stimulation improves gait in Parkinson's disease.Nature medicine · 2026Article
- A randomized controlled trial protocol of herbal formulas for modifying susceptible body constitution to enhance COVID-19 resistance in Hong Kong residents.Journal of thoracic disease · 2026Article
- Adaptive Deep Brain Stimulation for Parkinson's Disease: Navigating the Roadblocks to Clinical Implementation.Movement disorders : official journal of the Movement Disorder Society · 2026Review
- Double Fault: Artifacts Produced by Physical Activity Can Impact the Efficacy of Chronic Local Field Potential Recordings and Adaptive Stimulation.Movement disorders clinical practice · 2026Article
- Clinical utility of evoked potentials for programming subthalamic deep brain stimulation in Parkinsons disease.NPJ Parkinson's disease · 2026Review
- Low-frequency activity in the subthalamic nucleus informs about the acute neuropsychiatric state in Parkinson's disease.NPJ Parkinson's disease · 2026Article
- From synapse to system: mechanistic pathways of neural signaling dysfunction in psychiatric disorders.Frontiers in cell and developmental biology · 2026Review
- Local Field Potentials in Movement Disorders: A Narrative Review.Stereotactic and functional neurosurgery · 2026Review
- Local field potential biomarkers for adaptive deep brain stimulation in Parkinson's disease: A scoping review.Surgical neurology international · 2026Review
- The application of AI-driven digital phenotyping and interventions in neuropsychiatric disorders.Frontiers in psychiatry · 2026Review
- Being Guided by Your Brain or by Your Heart? Challenges in Adaptive Deep Brain Stimulation.Movement disorders clinical practice · 2026Article
- Ethical considerations of deep brain stimulation for treatment refractory schizophrenia: surveying stakeholders.BMC psychiatry · 2025Article
- Effect of deep brain stimulation on dysphagia in Parkinson's disease: mechanisms, evidence, and outlook.Frontiers in aging neuroscience · 2025Review
Corrections and comments
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Authors and funding
27 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
While conventional deep brain stimulation (cDBS) treatment delivers continuous electrical stimuli, new adaptive DBS (aDBS) technology provides dynamic symptom-related stimulation. Research data are promising, and devices are already available, but are we ready for it? We asked leading DBS experts worldwide (n = 21) to discuss a research agenda for aDBS research in the near future to allow full adoption. A 5-point Likert scale questionnaire, along with a Delphi method, was employed. In the next 10 years, aDBS will be clinical routine, but research is needed to define which patients would benefit more from the treatment; second, implantation and programming procedures should be simplified to allow actual generalized adoption; third, new adaptive algorithms, and the integration of aDBS paradigm with new technologies, will improve control of more complex symptoms. Since the next years will be crucial for aDBS implementation, the research should focus on improving precision and making programming procedures more accessible.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.