ArticleIndian journal of pharmacology2025
An unusual and interesting case of sequential serious adverse event.
Article in Indian journal of pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
abstractHydrocortisone and pheniramine are frequently administered drugs for the management of severe allergic or anaphylactic reactions. However, there is hardly any literature that shows the association between the use of these drugs for the management of anaphylactic reactions that can induce serious adverse effect. We present a peculiar case of loss of consciousness following concurrent administration of intravenous pheniramine (Avil) and hydrocortisone (primacort) for the management of another drug-induced adverse reaction characterized by urticaria and pruritis that erupted succeeding intake of a fluoroquinolone group of the drug (ofloxacin). Loss of consciousness associated with pheniramine is a serious adverse drug reaction and its association was found out to be "probable/likely" according to the WHO-UMC Causality Assessment Scale. Such reactions, although rare, can be serious requiring immediate hospitalization and warrant vigilance.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.