Evidence map›Paper›PMID 40324796›Full record

ArticleAddiction biology2025

Reduced Sensitivity to Negative Feedback May Lead to Risky Decision-Making in Amphetamine Users.

Yu-Hua Liu, Chiao-Yun Chen, Neil G Muggleton

Abstract read
In one paragraph

Article in Addiction biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yu-Hua LiuDepartment of Criminology, National Chung Cheng University, Chiayi, Taiwan.ORCID 0000-0002-9018-141X
Chiao-Yun ChenDepartment of Criminology, National Chung Cheng University, Chiayi, Taiwan.
Neil G MuggletonCognitive Intelligence and Precision Healthcare Center, National Central University, Taoyuan, Taiwan.

Funding

National Science and Technology Council (NSTC), Taiwan 109-2410-H-194-037National Science and Technology Council (NSTC), Taiwan 110-2410-H-008-040-MY3National Science and Technology Council (NSTC), Taiwan 110-2410-H-194-061National Science and Technology Council (NSTC), Taiwan 111-2410-H-194-072-MY2
6 · The paper itself

Abstract

In Taiwan, amphetamines are the main drug of abuse. While drug abuse is often related to individual risky decision-making, how this relates to underlying neural mechanisms in amphetamine abusers remains unclear. The current study was carried out to help better understand this. A Balloon Analogue Risk Task (BART) was used to examine individual risky decision-making in conjunction with event-related potential (ERP) recording and presentation of questionnaires relating to behavioural control. Compared with healthy controls, amphetamine users had a lower score on the Behavioural Inhibition System (BIS) scale and showed reduced amplitudes in feedback-related negativity (FRN) and error-related negativity (ERN) ERP components following negative feedback on the task. Amphetamine users were less sensitive to punitive or aversive stimuli. This reduced sensitivity might lead to a higher tendency for risky decision-making, with them less able to learn from mistakes and thus repeatedly engage in risky behaviours.

Indexed as

Amphetamine-Related DisordersDecision MakingFeedback, PsychologicalRisk-TakingAdultElectroencephalographyEvoked PotentialsFemaleHumansInhibition, PsychologicalMaleTaiwanYoung AdultamphetamineBalloon Analogue Risk Task (BART)Behavioural Inhibition System (BIS)ERNFRNrisking decision making

Identifiers

PMID40324796
PMCPMC12052401

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.