Evidence map›Paper›PMID 40324648›Full record

ArticleNeuropharmacology2025

Activation of anoctamin-1 calcium-activated chloride channels reduces voluntary alcohol consumption in rats.

Gleice Kelli Silva-Cardoso, Prosper N'Gouemo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuropharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Gleice Kelli Silva-CardosoHoward University College of Medicine, Department of Physiology and Biophysics, Washington, DC, 20059, United States of America.
Prosper N'GouemoHoward University College of Medicine, Department of Physiology and Biophysics, Washington, DC, 20059, United States of America. Electronic address: prosper.ngouemo@howard.edu.

Funding

Na+/Ca2+ exchanger remodeling in alcohol withdrawal seizuresR01AA027660 · NIAAA · HOWARD UNIVERSITY · PI N'GOUEMO, PROSPER · 2019 to 2023
$1.7M
NIAAA NIH HHS R01 AA027660
6 · The paper itself

Abstract

Repeated episodes of binge drinking can lead to an alcohol use disorder, yet the underlying pharmacological mechanisms are still not fully understood. Nevertheless, emerging evidence indicates that Ca

Indexed as

Alcohol DrinkingAnoctamin-1Chloride Channel AgonistsAnimalsDose-Response Relationship, DrugDrinkingEthanolFemaleMaleRatsRats, Sprague-DawleyANO1 protein, ratAnoctamin-1Chloride Channel AgonistsEthanolAlcohol intakeAlcohol preferenceEACTT16Ainh-A01TMEM16A channelWater intake

Identifiers

PMID40324648
PMCPMC12172797

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.