ArticleEnvironmental science & technology2025
Application of a Non-targeted Biomonitoring Method to Characterize Occupational Chemical Exposures of Women Nurses Relative to Office Workers.
Article in Environmental science & technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Breast cancer-related occupational exposures facing immigrant women.Journal of exposure science & environmental epidemiology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We analyzed blood serum samples from two unique female occupational cohorts - 60 nurses and 40 office workers in San Francisco, CA - using liquid chromatography and high-resolution mass spectrometry (quadrupole time-of-flight). Applying a nontargeted analysis (NTA) approach, we sought to isolate occupationally related chemical exposures that were unique to nurses by flagging features that were different from office workers in abundance (mean; 95th percentile) or detection frequency. Of 9828 negative electrospray ionization (ESI-) and 6898 positive electrospray ionization (ESI+) detected chemical features, 1094 and 938, respectively, were higher in nurses, possibly due to workplace exposures. We deciphered the molecular structures of these chemical features by applying data-dependent acquisition (DDA) and targeted MS/MS approaches to pooled samples from each occupational group, and we annotated them using spectral MS/MS databases in MS-DIAL. Nurses had higher concentrations of 14 chemicals that we identified at Schymanski Level 1 (N = 6) or 2 (N = 8), as well as 20 tentatively identified chemicals without spectra. Several chemicals may be occupationally relevant for nurses, including a PFAS (6:2 fluorotelomer sulfonic acid), tridecanedioic acid, salicylic acid, and the medications acetaminophen and theophylline. To our knowledge, this study is the first to apply NTA to elucidate novel chemical exposures in nurses.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.