Evidence map›Paper›PMID 40324144›Full record

ArticleEnvironmental health perspectives2025

Air Pollution and Autism Spectrum Disorder: Unveiling Multipollutant Risks and Sociodemographic Influences in California.

Karl O'Sharkey, Sanjali Mitra, Ting Chow, Laura Thompson, Jason Su, Myles Cockburn, Beate Ritz

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Environmental health perspectives, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Karl O'SharkeyDepartment of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, California, USA.ORCID 0000-0002-7439-8811
Sanjali MitraDepartment of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, California, USA.
Ting ChowDepartment of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, California, USA.
Laura ThompsonDepartment of Population and Public Health Sciences, University of Southern California, Los Angeles, California, USA.
Jason SuDivision of Environmental Health Sciences, School of Public Health, University of California Berkeley, Berkeley, California, USA.
Myles CockburnDepartment of Population and Public Health Sciences, University of Southern California, Los Angeles, California, USA.
Beate RitzDepartment of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, California, USA.ORCID 0000-0001-6976-7339

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAutism spectrum disorder (ASD) is a neurodevelopmental condition with increasing prevalence worldwide. Air pollution may be a major contributor to the rise in ASD cases. This study investigated how the risk of ASD associated with prenatal and early postnatal exposure to specific air pollutants is modified by key sociodemographic factors, exploring vulnerable exposure periods.

methodsWe conducted a California population-based cohort study of 44,173 ASD cases among 2,371,379 children born between 2013 and 2018 (California birth registry), linked to California Department of Developmental Services (DDS) records to extract ASD diagnoses prior to the end of 2022. Prenatal and 1-year postnatal air pollution exposures [fine particulate matter with aerodynamic diameter

resultsPrenatal and postnatal

conclusionsExposure to specific air pollutants during pregnancy and in the postnatal periods is associated with an increased risk of ASD, with sociodemographic differences potentially highlighting exposure hot spots and sources as well as subpopulation vulnerabilities. https://doi.org/10.1289/EHP15573.

Indexed as

Air PollutantsAir PollutionAutism Spectrum DisorderEnvironmental ExposurePrenatal Exposure Delayed EffectsCaliforniaChildChild, PreschoolCohort StudiesFemaleHumansInfantMaleNitrogen DioxideOzoneParticulate MatterAir PollutantsNitrogen DioxideOzoneParticulate Matter

Identifiers

PMID40324144
PMCPMC12161453

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.