Evidence map›Paper›PMID 40323787›Full record

ReviewAmerican journal of physiology. Gastrointestinal and liver physiology2025

Liver bypass in the development of pathogen-associated pulmonary vascular disease: contribution of mesocaval and portosystemic shunts.

Claudia Lucia Martins Silva, Prasanth N Puthanveetil, Suellen Darc Oliveira

Abstract readReview
In one paragraph

Review in American journal of physiology. Gastrointestinal and liver physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Claudia Lucia Martins SilvaBiochemical and Molecular Pharmacology Laboratory, Institute of Biomedical Sciences, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.ORCID 0000-0001-9227-6036
Prasanth N PuthanveetilChicago College of Osteopathic Medicine, Midwestern University, Downers Grove, Illinois, United States.ORCID 0000-0002-6390-3974
Suellen Darc OliveiraVascular Immunobiology Laboratory, Department of Anesthesiology, College of Medicine, University of Illinois Chicago, Chicago, Illinois, United States.ORCID 0000-0002-7654-1909

Funding

Generation of Endothelial Cell Memory in Inflammatory Vascular DiseaseK01HL159037 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI DOS SANTOS OLIVEIRA, SUELLEN D'ARC · 2021 to 2025
$800k
CNPq | Instituto Nacional de Ciência e Tecnologia da Criosfera (INCT da Criosfera) CNPq 312051/2023-9HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) HL159037NHLBI NIH HHS K01 HL159037
6 · The paper itself

Abstract

Portosystemic and mesocaval shunts are aberrant vascular connections that bypass hepatic detoxification process, directly linking the portal to the systemic circulation. These shunts, whether congenital or acquired, might play a pivotal role in the pathogenesis of systemic inflammatory diseases, such as schistosomiasis-associated pulmonary hypertension (Sch-PH) by facilitating the dissemination of pathogen-derived eggs and antigens from the gut and mesentery into the lungs. Beyond the translocation of

Indexed as

Hypertension, PortalHypertension, PulmonaryLiverSchistosomiasisAnimalsHumansgut-lung microbiomemesenteryportal hypertensionportosystemic shuntspulmonary hypertension

Identifiers

PMID40323787
PMCPMC12199453

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.