Evidence map›Paper›PMID 40323469›Full record

ArticleMolecular imaging and biology2025

Radiomic Analysis of Striatal [

Astrid Schiulaz, Giovanna Nordio, Alessio Giacomel, Rubaida Easmin, Andrea Bettinelli, Pierluigi Selvaggi, Steven Williams, Federico Turkheimer, Sameer Jauhar, Oliver Howes and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular imaging and biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Astrid SchiulazDepartment of Information Engineering, University of Padua, Padua, Italy.
Giovanna NordioDepartment of Neuroimaging, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Alessio GiacomelDepartment of Neuroimaging, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Rubaida EasminDepartment of Neuroimaging, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Andrea BettinelliMedical Physics Department, Veneto Institute of Oncology IOV - IRCCS, Padova, Italy.
Pierluigi SelvaggiDepartment of Neuroimaging, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Steven WilliamsDepartment of Neuroimaging, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Federico TurkheimerDepartment of Neuroimaging, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Sameer JauharDepartment of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Oliver HowesDepartment of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Mattia VeroneseDepartment of Information Engineering, University of Padua, Padua, Italy. mattia.veronese@kcl.ac.uk.ORCID http://orcid.org/0000-0003-3562-0683
FDOPA PET Imaging Working Group

Funding

Ministero dell'Istruzione, dell'Università e della Ricerca 2022RXM3H7Ministero dell'Istruzione, dell'Università e della Ricerca CN00000013 CN1Ministero dell'Istruzione, dell'Università e della Ricerca PNC0000002_DAREWellcome TrustWellcome Trust 215747/Z/19/Z
6 · The paper itself

Abstract

purposeSchizophrenia (SCZ) is a severe psychiatric disorder marked by abnormal dopamine synthesis, measurable through [

methodsWe analysed 273 [

resultsOut of 177 features, 15 met the ICC criteria (ICC: 0.81-0.99). Age and sex influenced features in patients but not in controls. The best performance were was by the GLCM joint maximum feature, which effectively differentiated responders from non-responders (AUC: 0.66-0.87), but did not reach statistical significance in classification over SUVr.

conclusionRadiomic analysis of [

Indexed as

Antipsychotic AgentsDihydroxyphenylalaninePositron-Emission TomographyPsychotic DisordersAdultCase-Control StudiesFemaleHumansMaleMiddle AgedRadiomicsReproducibility of ResultsSchizophreniaTreatment OutcomeYoung AdultAntipsychotic AgentsDihydroxyphenylalaninefluorodopa F 18FDOPAPETRadiomicsSchizophrenia

Identifiers

PMID40323469
PMCPMC12162767

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.