ArticleIntensive care medicine2025
Renal tubular epithelial cells as an easily accessible biomarker for diagnosing AKI post cardiac surgery.
Article in Intensive care medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- What new renal biomarkers tell us about renal physiology: Collection: physiology applied to ICU.Annals of intensive care · 2026Review
- Acute Kidney Injury Biomarkers in Perioperative Care: A Scoping Review of Clinical Implementation.Diagnostics (Basel, Switzerland) · 2025Review
- Update on acute kidney injury: some progresses and a long way to go.Intensive care medicine · 2025Article
- Response to the Letter to the Editor Entitled "Renal Tubular Epithelial Cells as Marker of Tubular Damage in Acute Kidney Disease".Kidney international reports · 2025Article
- Renal Tubular Epithelial Cells as Marker of Tubular Damage in Acute Kidney Disease.Kidney international reports · 2025Article
- Renal tubular epithelial cells: A revived kidney biomarker?Intensive care medicine · 2025Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeAcute kidney injury (AKI) is a common clinical complication of cardiac surgeries. Although urinary particle analysis is useful for differentiating AKI, its value in AKI diagnosis has not yet been well described. We sought to determine the contribution of urinary particle analysis to the diagnosis of AKI.
methodsTwo-hundred and thirty-nine adult patients were prospectively included after cardiac surgery. The diagnostic performance of urinary particle analysis at different time points after intensive care unit (ICU) admission was evaluated. AKI was diagnosed and classified according to the KDIGO definitions. Urinary particles, including renal tubular epithelial cells (RTEC) and non-hyaline casts, Nephrocheck
resultsOf the 239 patients included, 39 (16.3%) had AKI stage 1, 121 (50.6%) had stage 2, and 15 (6.3%) stage 3. In the early postoperative period, urinary alpha-1-microglobulin and Nephrocheck
conclusionUrinary particle analysis with RTEC is useful for the early diagnosis of AKI following cardiac surgery, especially at 12 h and 24 h after ICU admission.
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