Evidence map›Paper›PMID 40323440›Full record

ReviewBiotechnology letters2025

Metabolic response of Bacillus spp. to heavy metal stress: pathway alterations and metabolite profiles.

Xiaowen Yang, Xiaotong Lin, Zhenglin Zhou, Bokun Lin, Xin Liu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Biotechnology letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xiaowen YangDongguan Key Laboratory of Public Health Laboratory Science, School of Public Health, Guangdong Medical University, Dongguan, 523808, China.
Xiaotong LinDongguan Key Laboratory of Public Health Laboratory Science, School of Public Health, Guangdong Medical University, Dongguan, 523808, China.
Zhenglin ZhouDongguan Key Laboratory of Public Health Laboratory Science, School of Public Health, Guangdong Medical University, Dongguan, 523808, China.
Bokun LinDongguan Key Laboratory of Public Health Laboratory Science, School of Public Health, Guangdong Medical University, Dongguan, 523808, China. bklin@gdmu.edu.cn.
Xin LiuDongguan Key Laboratory of Public Health Laboratory Science, School of Public Health, Guangdong Medical University, Dongguan, 523808, China. lx@gdmu.edu.cn.ORCID http://orcid.org/0009-0006-2118-3549

Funding

Guangdong Basic and Applied Basic Research Foundation 2019A1515110994National Natural Science Foundation of China 32201983
6 · The paper itself

Abstract

Heavy metal pollution is a global issue that poses significant risks to ecosystems and human health. Microorganisms offer a promising bioremediation approach due to their ability to mitigate metal-induced metabolic damage in an eco-friendly, efficient, and cost-effective manner. Among them, Gram-positive Bacillus species exhibit a high heavy metal adsorption capacity and secrete metabolites with diverse functional properties. Under heavy metal stress, these metabolites play a crucial role in alleviating metal-induced damage. However, the application of Bacillus metabolites in heavy metal remediation faces challenges, including prolonged treatment durations, the necessity for stable environmental conditions, and specific nutrient requirements.This review summarizes recent research on the effects of heavy metal exposure on the metabolic pathways and metabolites of Bacillus spp., elucidates their role in influencing metal bioavailability and chemical transformations, and explores innovative strategies to enhance the stability of Bacillus-mediated heavy metal remediation. The review aims to provide valuable insights for optimizing bioremediation strategies, facilitating the selection of efficient degrading strains, and advancing the sustainable management of heavy metal contamination.

Indexed as

BacillusMetabolic Networks and PathwaysMetabolomeMetals, HeavyBiodegradation, EnvironmentalStress, PhysiologicalMetals, HeavyBacillusHeavy metalMetabolismRepair

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.