Evidence map›Paper›PMID 40323439›Full record

ArticlePediatric radiology2025

Hui Sun, Zhiyong Yang, Hongfu Jin, Yanfen Cui, Yafu Yin, Suyun Chen, Chenglai Fu, Hui Wang, Weiwei Cheng

Abstract read
PubMed Publisher
In one paragraph

Article in Pediatric radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Reply to Littooij AS.Pediatric radiology · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hui Sun *Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 1665 Kongjiang Road, 200092, China.
Zhiyong Yang *Chongming Hospital Affiliated to Shanghai University of Medicine and Health Sciences, Shanghai, China.
Hongfu JinXinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 1665 Kongjiang Road, 200092, China.
Yanfen CuiCancer Hospital Affiliated to Shanxi Medical University, Taiyuan, China.
Yafu YinXinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 1665 Kongjiang Road, 200092, China.
Suyun ChenXinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 1665 Kongjiang Road, 200092, China.
Chenglai FuXinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 1665 Kongjiang Road, 200092, China.
Hui WangXinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 1665 Kongjiang Road, 200092, China. wanghui@xinhuamed.com.cn.
Weiwei ChengXinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 1665 Kongjiang Road, 200092, China. chengweiwei8416@xinhuamed.com.cn.

Funding

National Natural Science Foundation of China 81901162Natural Science Foundation of Shanghai Municipality 23ZR1441200
6 · The paper itself

Abstract

backgroundClear cell sarcoma of the kidney is a rare primary renal malignancy in children and its differentiation from other renal tumors, particularly Wilms' tumor, poses significant diagnostic challenges. Notably, clear cell sarcoma of the kidney is associated with a poorer prognosis than Wilms' tumor, making the preoperative presumptive diagnosis critical for optimizing surgical resection and appropriate chemotherapy regimens.

objectiveWe conducted a feasibility study to evaluate the diagnostic utility of MATERIALS AND

methodsThis study included 19 patients diagnosed with clear cell sarcoma of the kidney and 84 patients with Wilms' tumor. Among these, 11/19 patients with clear cell sarcoma of the kidney and 28/84 patients of Wilms' tumor displayed positive findings on

resultsThe mean SUVmax for all lesions of clear cell sarcoma of the kidney was significantly lower than that of Wilms' tumors (3.9 vs. 7.4; P<0.001). When analyzed separately, primary lesions (3.6 vs. 6.6; P=0.042) and metastatic lesions (4.0 vs. 7.8; P=0.011) both had lower SUVmax in clear cell sarcomas of the kidney compared with Wilms' tumors. ROC curve analysis revealed a cutoff SUVmax of 4.3, which effectively supported the diagnosis of clear cell sarcoma of the kidney over Wilms' tumor, with a sensitivity of 75.0% and a specificity of 87.5%.

conclusionsClear cell sarcomas of the kidney exhibited a significantly lower SUVmax on

Indexed as

Fluorodeoxyglucose F18Kidney NeoplasmsPositron Emission Tomography Computed TomographySarcoma, Clear CellWilms TumorAdolescentChildChild, PreschoolDiagnosis, DifferentialFeasibility StudiesFemaleHumansInfantMaleRadiopharmaceuticalsRetrospective StudiesFluorodeoxyglucose F18RadiopharmaceuticalsClear cell sarcoma of the kidneyDiagnosisFluorodeoxyglucose positron emission tomography/computed tomographyPediatric renal tumorWilms’ tumor

Identifiers

PMID40323439

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.