Evidence map›Paper›PMID 40323419›Full record

ReviewHandbook of experimental pharmacology2025

Advanced Mass Spectrometry Techniques for the Characterization of Carbohydrates.

Niklas Geue, Caitlin Walton-Doyle, Eleonora Renzi, Mathew Bejoy, Kevin Pagel

Abstract readReview
PubMed Publisher
In one paragraph

Review in Handbook of experimental pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Niklas GeueInstitute of Chemistry and Biochemistry, Freie Universität Berlin, Berlin, Germany.
Caitlin Walton-DoyleInstitute of Chemistry and Biochemistry, Freie Universität Berlin, Berlin, Germany.
Eleonora RenziInstitute of Chemistry and Biochemistry, Freie Universität Berlin, Berlin, Germany.
Mathew BejoyInstitute of Chemistry and Biochemistry, Freie Universität Berlin, Berlin, Germany.
Kevin PagelInstitute of Chemistry and Biochemistry, Freie Universität Berlin, Berlin, Germany. kevin.pagel@fu-berlin.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mass spectrometry-based techniques have emerged as a gamechanger for the analysis of carbohydrates. Here, we summarize state-of-the-art glycan analysis in vacuo, demonstrating how mass spectrometry, tandem mass spectrometry, ion mobility spectrometry, and gas-phase infrared spectroscopy, supported by chromatography methods and computational modelling, facilitate the structural characterization of isolated glycans and the analysis of the entire glycome. After an introduction to glycans and techniques, the sugar classes of N-glycans, O-glycans, human milk oligosaccharides, and glycosaminoglycans will be discussed in detail, before the chapter ends with an outlook on the future of mass spectrometry-based glycan analysis.

Indexed as

CarbohydratesMass SpectrometryPolysaccharidesAnimalsGlycomicsGlycosaminoglycansHumansIon Mobility SpectrometryMilk, HumanOligosaccharidesTandem Mass SpectrometryCarbohydratesGlycosaminoglycansOligosaccharidesPolysaccharidesGas-phase infrared spectroscopyGlycosaminoglycansHuman milk oligosaccharidesIon mobility spectrometryN-glycansO-glycansTandem mass spectrometry

Identifiers

PMID40323419

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.