Evidence map›Paper›PMID 40323381›Full record

ArticleAbdominal radiology (New York)2025

A case of uterine leiomyosarcoma in a survivor of hereditary retinoblastoma.

Mitsuhiro Kirita, Yuki Himoto, Yuka Kuriyama Matsumoto, Yasuhisa Kurata, Aki Kido, Yusuke Yamaoka, Koji Yamanoi, Masaki Mandai, Sachiko Minamiguchi, Yuji Nakamoto

Abstract readCase Reports
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In one paragraph

Article in Abdominal radiology (New York), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mitsuhiro KiritaKyoto University, Kyoto, Japan.
Yuki HimotoKyoto University, Kyoto, Japan. yhimoto@kuhp.kyoto-u.ac.jp.
Yuka Kuriyama MatsumotoKyoto University, Kyoto, Japan.
Yasuhisa KurataKyoto University, Kyoto, Japan.
Aki KidoUniversity of Toyama, Toyama, Japan.
Yusuke YamaokaKyoto University, Kyoto, Japan.
Koji YamanoiKyoto University, Kyoto, Japan.
Masaki MandaiKyoto University, Kyoto, Japan.
Sachiko MinamiguchiFujita Health University, Toyoake, Japan.
Yuji NakamotoKyoto University, Kyoto, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Survivors of hereditary retinoblastoma have increased risk of subsequent primary malignancies due to RB1 mutation. We report uterine leiomyosarcoma (LMS) in a hereditary retinoblastoma survivor. She had follow-up for leiomyomas, with pelvic MRI showing typical leiomyomas two years prior. She presented with abdominal distention, and MRI revealed a massive tumor with LMS characteristics where a leiomyoma was previously observed. Chest CT showed a nodule suspicious for metastasis in the left lung. Total hysterectomy with bilateral salpingo-oophorectomy and partial lung resection was performed. Pathology confirmed LMS with pulmonary metastasis. Immunostaining showed complete RB1 loss in tumor cells. LMS was suspected to have arisen near a pre-existing leiomyoma or resulted from its malignant transformation. Continuous follow-up is necessary in hereditary retinoblastoma survivors.

Indexed as

LeiomyosarcomaNeoplasms, Second PrimaryRetinal NeoplasmsRetinoblastomaUterine NeoplasmsFemaleHumansHysterectomyLung NeoplasmsMagnetic Resonance ImagingTomography, X-Ray ComputedHereditary retinoblastomaLeiomyomaMagnetic resonance imaging (MRI)Malignant transformationSecondary malignancyUterine leiomyosarcoma

Identifiers

PMID40323381

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.