ArticlePsychophysiology2025
Dual-Site Beta tACS Over the rIFG and preSMA-Induced Phase-Specific Changes in Functional Connectivity but not Response Inhibition Performance in Older Adults.
Article in Psychophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Bifocal Beta-frequency Transcranial Alternating Current Stimulation Enhances Somatosensory Spatial Discrimination.Brain topography · 2026Article
- Phase-Specific Dual-Site Beta Transcranial Alternating Current Stimulation Differentially Influences Functional Connectivity Associated With Motor Inhibition Performance.Human brain mapping · 2026Article
- Variable E-field properties of dual-site tACS with phase lags.Imaging neuroscience (Cambridge, Mass.) · 2026Article
- Multifocal transcranial electrical stimulation to enhance cognitive functions: a systematic review.Frontiers in neuroscience · 2025Review
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Research suggests that changes in functional connectivity contribute to age-related declines in response inhibition. Through a double-blind crossover study, we investigated the effects of dual-site beta transcranial alternating current stimulation (tACS) over the right inferior frontal gyrus (rIFG) and pre-supplementary motor area (preSMA) on functional connectivity measured with electroencephalography and response inhibition (stop-signal task performance) in 15 older (aged 61-79 years) and 18 young (aged 18-34 years) adults. Two tACS conditions were administered in separate sessions: in-phase tACS, where electrical currents delivered to rIFG and preSMA had a 0° phase difference, and anti-phase tACS, where currents had a 180° phase difference. Resting-state beta band rIFG-preSMA connectivity significantly increased after in-phase tACS for older and young adults and decreased after anti-phase tACS for older adults. Response inhibition significantly improved after both in- and anti-phase tACS for young and older adults. These findings suggest that tACS can potentially modulate rIFG-preSMA connectivity in a phase-specific manner in the aging brain, and that inhibitory performance might not be directly regulated by resting-state rIFG-preSMA phase connectivity. Due to the lack of sham control, placebo effects cannot be ruled out. However, the differing neurophysiological effects from in- and anti-phase tACS suggest that rIFG-preSMA resting-state phase connectivity is unlikely to underpin the changes in inhibitory performance. Future studies incorporating a sham control are required to verify these findings.
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