Evidence map›Paper›PMID 40322604›Full record

ArticleCureus2025

A Practice Model for Palliative Radiotherapy.

Alina Zheng, Alec Zheng, Alan Zheng, Xiaodong Wu, Beatriz Amendola

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alina ZhengRadiation Oncology, Innovative Cancer Institute, South Miami, USA.
Alec ZhengRadiation Oncology, Innovative Cancer Institute, South Miami, USA.
Alan ZhengRadiation Oncology, Innovative Cancer Institute, South Miami, USA.
Xiaodong WuRadiation Oncology, Innovative Cancer Institute, South Miami, USA.
Beatriz AmendolaRadiation Oncology, Innovative Cancer Institute, South Miami, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite well-recognized challenges in implementing palliative radiation therapy (PRT), progress remains slow, and conventional approaches have yielded limited success. A transformative strategy is required to overcome systemic barriers and establish a sustainable PRT infrastructure. This proposal presents a novel model to improve accessibility, affordability, and integration into palliative care by addressing key obstacles in training, regulation, facility development, and treatment protocols. A specialized certification track within radiation oncology residency programs is proposed, enabling palliative care physicians to obtain limited PRT licenses under the supervision of fully licensed radiation oncologists. Regulatory adjustments should facilitate this framework, ensuring compliance while expanding the PRT workforce. Dedicated PRT facilities-affiliated with comprehensive radiation therapy centers (CRTCs) and integrated into hospice settings-will enhance accessibility by reducing logistical and financial burdens. These facilities will utilize cost-effective infrastructure, including refurbished linear accelerators, modular construction, and remote physics and dosimetry support, ensuring operational costs remain significantly lower than those of conventional radiotherapy centers. Optimizing PRT delivery requires shifting clinical strategies toward single-fraction treatment as the primary approach, followed by hypofractionation treatment when necessary. Systematic studies with a PRT-oriented mindset should establish PRT-specific treatment recommendations and recommendations, moving away from conventional radiation therapy protocols. By addressing key barriers in education, regulation, infrastructure, and clinical strategy, this model offers a path toward sustainable PRT implementation. While requiring initial investment and regulatory adjustments, it has the potential to improve end-of-life care for terminally ill cancer patients, ensuring greater dignity and comfort while establishing a robust foundation for future reimbursement models.

Indexed as

cancerhospicepain managementpalliative careradiotherapy

Identifiers

PMID40322604
PMCPMC12045645

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.