Evidence map›Paper›PMID 40322520›Full record

ArticleInternational journal of sports physical therapy2025

Symptom Duration is not Related to Central Sensitization Inventory in Midportion Achilles Tendinopathy.

Morgan N Potter, Hayley Powell Smitheman, Katie Butera, Ryan T Pohlig, Karin Grävare Silbernagel

Abstract read
In one paragraph

Article in International journal of sports physical therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Morgan N PotterDepartment of Physical Therapy University of Delaware.
Hayley Powell SmithemanDepartment of Physical Therapy University of Delaware.
Katie ButeraDepartment of Physical Therapy University of Delaware.
Ryan T PohligDepartment of Epidemiology University of Delaware.
Karin Grävare SilbernagelDepartment of Physical Therapy University of Delaware.

Funding

PT/PHD Predoctoral Training Program Diversity SupplementT32HD007490 · NICHD · UNIVERSITY OF DELAWARE · PI DARCY S. REISMAN · 1996 to 2026
$3.7M
Recovery of symptoms, function, tendon structure and mechanical properties in patients with Achilles Tendinopathy: A comparison between men and womenR01AR072034 · NIAMS · UNIVERSITY OF DELAWARE · PI GRAVARE SILBERNAGEL, KARIN M E · 2018 to 2022
$2.5M
NIAMS NIH HHS R01 AR072034NICHD NIH HHS T32 HD007490
6 · The paper itself

Abstract

Background: There is concern that the prolonged symptom duration commonly observed in Achilles tendinopathy may alter pain processing and lead to development of central sensitization. If true, presence of altered pain processing could explain why nearly one third of individuals with Achilles tendinopathy do not respond to gold standard treatment. Currently, the relationship between symptom duration, symptom severity, pain, and central sensitization in Achilles tendinopathy is unclear. Purpose: The purpose of this study was assess the proportion of individuals with midportion Achilles tendinopathy who may have central sensitization, as defined by the Central Sensitization Inventory (CSI) part A questionnaire. A secondary aim was to assess the relationship between symptom duration, pain intensity, symptom severity and CSI scores. Study Design: Cross-Sectional Study. Methods: Individuals diagnosed with midportion Achilles tendinopathy were included (n=182, 57% female (47.3±12.7 years). Bivariate correlations were used to evaluate relationships between symptom duration (time between date of symptom onset and date of study enrollment), symptom severity (assessed by Victorian Institute of Sport Assessment-Achilles, VISA-A), and pain intensity (assessed by Patient-Reported Outcomes Measurement Information System 29, PROMIS-29) with CSI scores. Results: Nine of 182 individuals (4.9%, 9 females) scored above the clinical cut off for CSI, indicating likely presence of central sensitization. Duration of symptoms did not correlate with CSI score (r = 0.037, 95% CI [-.109, .181] p=0.622). VISA-A had a significant negative correlation with CSI score (r=-0.293, [-.420, -.154] p<0.001), and pain intensity had a significant positive correlation with CSI score (r=0.195, [.051, .331] p=0.008). Conclusion: Less than five percent of individuals with midportion Achilles tendinopathy met criteria for likely presence of central sensitization as defined by the CSI screening questionnaire. The study findings suggest prolonged symptom duration among those with midportion Achilles tendinopathy is unlikely to increase the occurrence of symptoms associated with central sensitization. Level of Evidence: Level 4.

Indexed as

Achilles tendinitisnociplastic painpain intensityVISA-A

Identifiers

PMID40322520
PMCPMC12048355

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