Evidence map›Paper›PMID 40322457›Full record

ArticlePatient preference and adherence2025

Disease Impact and Perception of Biologics in Adults with Type 2 Inflammation Respiratory Disease: International Survey Results.

Ruth Tal-Singer, Kristen S Willard, Mark A Luttmann, Madison Sprankle, Jenna Reynolds, Irantzu Muerza Santos, Hannah Jaffee, Anna Vichiendilokkul, Cristina Jacomelli, Špela Novak and 2 more

Abstract read
In one paragraph

Article in Patient preference and adherence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ruth Tal-SingerGlobal Allergy & Airways Patient Platform, Hendersonville, TN, USA.ORCID 0000-0002-5275-8062
Kristen S WillardGlobal Allergy & Airways Patient Platform, Hendersonville, TN, USA.
Mark A LuttmannGlobal Allergy & Airways Patient Platform, Hendersonville, TN, USA.
Madison SprankleGlobal Allergy & Airways Patient Platform, Hendersonville, TN, USA.
Jenna ReynoldsAsthma Canada, Toronto, Ontario, Canada.
Irantzu Muerza SantosASMABI EUSKADI, Bilbao, Spain.
Hannah JaffeeAsthma and Allergy Foundation of America, Arlington, VA, USA.
Anna VichiendilokkulGSK, London, UK.ORCID 0009-0003-5168-1280
Cristina JacomelliAssociazione Nazionale Pazienti RESPIRIAMO INSIEME - APS, Padova, Italy.
Špela NovakGlobal Allergy & Airways Patient Platform, Vienna, Austria.
Victor Gascon MorenoGlobal Allergy & Airways Patient Platform, Vienna, Austria.
Robert A WiseJohns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID 0000-0002-8353-2349

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: There is a growing interest in developing approaches that reduce the impact of Type 2 inflammatory conditions, such as asthma and chronic rhinosinusitis with nasal polyps (CRSwNP), on well-being. The aim of this international survey was to understand the impact of asthma and CRSwNP on people living with these conditions and to seek insight into the perception of biologics, which are often used to treat them. Patients and Methods: A cross-sectional survey was conducted anonymously online from February to May 2024. International participants were recruited through social media and by Survey Monkey. Individuals aged ≥18 years diagnosed by a medical professional with asthma and/or CRSwNP who lived in the US, Canada, UK, Germany, Italy, France, or Spain were eligible to participate. Results: Of the 1566 survey participants (56.7% asthma, 24.8% CRSwNP, 18.5% both), 52.5% were female, and 65.3% were ages 25-54 years. Approximately two-thirds (64%) reported thinking once/day or at least once/week about managing their condition. Nearly half (44%) find it difficult to manage their disease. Of those currently using a biologic (14%), only 37% inject it themselves and feel confident doing so, and 42% felt it was a repeating reminder of their chronic condition. The top reason for stopping biologic treatment was that the injection/device was too difficult. The possibility of a lower frequency injection increased the likelihood participants would consider a biologic. Conclusion: The study further raises awareness of the personal burden from asthma and CRSwNP and their associated treatments in different countries. Beyond the goal of achieving clinical disease control for these diseases, a holistic approach to care delivery should include culturally appropriate emotional health support to improve overall well-being. Access to biologics administered with less frequency may alleviate some of the burden of self-injection.

Indexed as

asthmaburdenchronic rhinosinusitis with nasal polypsinjection

Identifiers

PMID40322457
PMCPMC12047282

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.