Evidence map›Paper›PMID 40322434›Full record

ArticleCureus2025

Necrotizing Fasciitis With Myonecrosis in a Diabetic Patient: Highlighting the Role of Early Detection and Management.

Bano Alsaleh, Ahmed Alanzi, Dawood Alatefi, Mohammed Alsaleh, Ahmed Alsaleh, Fouad Aladel

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Bano AlsalehRadiology, King Hamad University Hospital, Muharraq, BHR.
Ahmed AlanziAnesthesia and Critical Care, King Hamad University Hospital, Muharraq, BHR.
Dawood AlatefiFaculty of Medicine, University of Jordan Hashemite, Amman, JOR.
Mohammed AlsalehPediatric Medicine, Mohammed Bin Khalifa Bin Salman Al Khalifa Specialist Cardiac Centre, Awali, BHR.
Ahmed AlsalehFaculty of Medicine, Royal College of Surgeons in Ireland, Muharraq, BHR.
Fouad AladelRadiology, King Fahad Specialist Hospital Dammam, Dammam, SAU.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Necrotizing fasciitis (NF) is a life-threatening soft tissue infection that progresses rapidly and can lead to systemic complications. Myonecrosis, a severe complication of NF, involves muscle tissue death and often requires aggressive treatment. A 35-year-old female with diabetes mellitus, dyslipidemia, obesity, and a history of right breast cancer presented with acute, progressive right thigh pain, fever, and vomiting. Physical examination revealed local swelling, tenderness, warmth, and systemic signs of infection. Laboratory tests showed leukocytosis, elevated C-reactive protein, renal impairment, and hyponatremia. Contrast-enhanced MRI of the right thigh raised suspicion of NF with focal myonecrosis in the vastus lateralis and intermedius muscles. Surgical exploration and histopathology confirmed NF and myonecrosis. Debridement and broad-spectrum antibiotics, including vancomycin, meropenem, and clindamycin, were started. A second debridement and follow-up MRI showed improvement, with the patient recovering well and being discharged without complications. Early imaging, aggressive surgical intervention, and appropriate antibiotic therapy are critical in managing NF and myonecrosis, particularly in high-risk patients.

Indexed as

diabetesearly detectionimagingmyonecrosisnecrotizing fasciitis

Identifiers

PMID40322434
PMCPMC12050116

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.