ArticleCureus2025
Severe Malaria Infection Concurrent With Autoimmune Hemolytic Anemia and Acute Cytomegalovirus Infection: A Case Report.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Libman sacks endocarditis with multivalvular involvement, hemorrhagic stroke, and concurrent mixed plasmodium malaria in systemic lupus erythematosus: a case report.Journal of cardiothoracic surgery · 2026Article
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4 authors.
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Abstract
Malaria infection causes lysis of infected red blood cells (RBCs), leading to anemia. Autoimmune hemolytic anemia (AIHA), on the other hand, is caused by antibody-mediated destruction of RBCs, and it is associated with other autoimmune disorders like systemic lupus erythematosus (SLE). Thereby, we report a rare case of concurrent malaria infection with AIHA and acute cytomegalovirus (CMV) infection. A 33-year-old female presented with fever for seven days. She came back from Ethiopia 40 days ago. She was found to have severe anemia, and further workup revealed high levels of immunoglobulin G (IgG) antibodies against RBC. She rapidly improved with antimalarial and prednisolone therapy. She was also found to have immunoglobulin M (IgM) against CMV, indicating acute infection, but she didn't have specific manifestations related to CMV and therefore was not treated. During outpatient follow-up, she was found to have high antinuclear antibody (ANA) titers as well as low complements, indicating the possibility of an underlying autoimmune disorder. This case underscores the need for concurrent antimalarial and immunosuppressive therapy in co-occurring autoimmune hemolytic anemia (AIHA)/malaria, with close monitoring for SLE progression given high ANA titers.
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