Evidence map›Paper›PMID 40322415›Full record

ArticleCureus2025

Artificial Intelligence (AI)-Driven Adaptive Motion Management in Helical and Robotic Radiotherapy: Innovations, Challenges, and Future Directions.

Dhiren K Panda, Saurjya R Das, Shishir Kumar

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dhiren K PandaAnatomy, Institute of Medical Sciences (IMS) & SUM Hospital, Siksha 'O' Anusandhan University, Bhubaneswar, IND.
Saurjya R DasAnatomy, Institute of Medical Sciences (IMS) & SUM Hospital, Siksha 'O' Anusandhan University, Bhubaneswar, IND.
Shishir KumarAnatomy, Institute of Medical Sciences (IMS) & SUM Hospital, Siksha 'O' Anusandhan University, Bhubaneswar, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Artificial intelligence (AI) has revolutionized motion-adaptive radiotherapy (ART) by enhancing tumor-tracking accuracy and optimizing radiation dosage delivery. Traditional motion management techniques, such as respiratory gating and internal target volume (ITV) expansion, often result in increased treatment margins and unintended radiation exposure. AI-powered real-time motion tracking, deformable image registration (DIR), and ART offer superior tumor localization, automated dose modulation, and real-time imaging integration. This study examined AI-based motion guidance technologies in helical tomotherapy (HT) and CyberKnife (Accuray, Madison, WI) robotic radiosurgery, highlighting technical innovations, engineering challenges, and clinical applications. HT employs megavoltage computed tomography (MVCT) for intra-fractional motion monitoring, whereas CyberKnife utilizes x-ray-based beam correction via a robotic arm to achieve submillimeter precision. Despite advancements, challenges such as AI processing latency, tumor motion variability, and multimodal imaging integration persist. Future research should focus on improving the AI response times, enhancing motion prediction algorithms, and developing fully automated AI-based radiation delivery systems.

Indexed as

adaptive radiotherapyai-driven motion trackingcyberknife motion managementdeformable image registrationreal-time tumor tracking

Identifiers

PMID40322415
PMCPMC12050046

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.