Evidence map›Paper›PMID 40322398›Full record

ArticleCureus2025

A Case of Rocuronium-Induced Anaphylaxis Managed With Sugammadex.

Ahsum Khan, Kathleen Parr

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ahsum KhanAnesthesiology, George Washington University School of Medicine and Health Sciences, Washington D.C., USA.
Kathleen ParrAnesthesiology, George Washington University School of Medicine and Health Sciences, Washington D.C., USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anaphylaxis is a severe, life-threatening complication that can result in complete cardiovascular and respiratory collapse. Peri-operatively, this complication is most often seen after the intravenous (IV) induction of general anesthesia, and the most common responsible agents are non-depolarizing neuromuscular blocking agents. In this report, we describe a case of perioperative anaphylaxis induced by the non-depolarizing neuromuscular blocker rocuronium. Sugammadex, a reversal agent for the non-depolarizing muscle relaxants rocuronium and vecuronium, was administered shortly after induction. The patient showed rapid clinical improvement in blood pressure, heart rate, and oxygen saturation values within minutes of sugammadex administration. We suggest that sugammadex should be considered as an adjunct therapy when treating anaphylaxis caused by rocuronium.

Indexed as

anesthesia inductiondrug induced anaphylaxisperi-operative anaphylaxisrocuronium induced anaphylaxissugammadex

Identifiers

PMID40322398
PMCPMC12050028

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.