Evidence map›Paper›PMID 40322380›Full record

ArticleCureus2025

Primary Small Cell Cancer of the Breast: An Unusual Presentation.

Jay K Garlapati, Desten Howard, Jordan Maier, Michael C Joiner, Steven R Miller

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jay K GarlapatiDepartment of Oncology, Wayne State University School of Medicine, Detroit, USA.
Desten HowardDepartment of Pathology, Wayne State University School of Medicine, Detroit, USA.
Jordan MaierDepartment of Oncology, Wayne State University School of Medicine, Detroit, USA.
Michael C JoinerDepartment of Oncology, Wayne State University School of Medicine, Detroit, USA.
Steven R MillerDepartment of Oncology, Wayne State University School of Medicine, Detroit, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary small cell carcinoma of the breast (PSCCB) is a rare but aggressive disease with multiple treatment options available, including surgery, chemotherapy, and radiation therapy. We report a case of a 51-year-old female patient who presented with a palpable left breast mass. An ultrasound-guided core needle biopsy of the affected area revealed triple-negative small cell carcinoma of the left breast. The patient underwent neoadjuvant chemotherapy, breast-conserving surgery with negative margins, and post-operative radiation therapy. One year later, the patient developed pathologic evidence of metastatic disease. Despite receiving three additional chemotherapeutic regimens and site-specific radiation treatments, the patient continued to have widespread metastatic disease. This case underscores the challenges of diagnosing and treating PSCCB and the urgent need for creating a standardized treatment protocol to improve patient outcomes.

Indexed as

external radiation therapyintensive chemotherapyneuroendocrine carcinoma (nec)rare breast cancersmall cell carcinomas

Identifiers

PMID40322380
PMCPMC12050075

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.