Evidence map›Paper›PMID 40322052›Full record

ArticleGlobal heart2025

Impact of Bicytopenia on Mortality in Hospitalised Patients With Heart Failure.

Toshitaka Okabe, Tadayuki Yakushiji, Daiki Kato, Hirotoshi Sato, Toshihiko Matsuda, Yui Koyanagi, Katsuya Yoshihiro, Takeshi Okura, Yuma Gibo, Yuki Ito and 8 more

Abstract read
In one paragraph

Article in Global heart, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Toshitaka OkabeDivision of Cardiology, Showa University Northern Yokohama Hospital, Yokohama, Japan.ORCID 0000-0001-9687-9256
Tadayuki YakushijiDivision of Cardiology, Showa University Northern Yokohama Hospital, Yokohama, Japan.
Daiki KatoDivision of Cardiology, Showa University Northern Yokohama Hospital, Yokohama, Japan.
Hirotoshi SatoDivision of Cardiology, Showa University Northern Yokohama Hospital, Yokohama, Japan.
Toshihiko MatsudaDivision of Cardiology, Showa University Northern Yokohama Hospital, Yokohama, Japan.
Yui KoyanagiDivision of Cardiology, Showa University Northern Yokohama Hospital, Yokohama, Japan.
Katsuya YoshihiroDivision of Cardiology, Showa University Northern Yokohama Hospital, Yokohama, Japan.
Takeshi OkuraDivision of Cardiology, Showa University Northern Yokohama Hospital, Yokohama, Japan.
Yuma GiboDivision of Cardiology, Showa University Northern Yokohama Hospital, Yokohama, Japan.ORCID 0009-0002-8360-1946
Yuki ItoDivision of Cardiology, Showa University Northern Yokohama Hospital, Yokohama, Japan.
Tatsuki FujiokaDivision of Cardiology, Showa University Northern Yokohama Hospital, Yokohama, Japan.
Shigehiro IshigakiDivision of Cardiology, Showa University Northern Yokohama Hospital, Yokohama, Japan.
Shuro NaruiDivision of Cardiology, Showa University Northern Yokohama Hospital, Yokohama, Japan.
Taro KimuraDivision of Cardiology, Showa University Northern Yokohama Hospital, Yokohama, Japan.
Suguru ShimazuDivision of Cardiology, Showa University Northern Yokohama Hospital, Yokohama, Japan.
Yuji OyamaDivision of Cardiology, Showa University Northern Yokohama Hospital, Yokohama, Japan.
Naoei IsomuraDivision of Cardiology, Showa University Northern Yokohama Hospital, Yokohama, Japan.ORCID 0000-0001-6225-0281
Masahiko OchiaiDivision of Cardiology, Showa University Northern Yokohama Hospital, Yokohama, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Limited data are available on bicytopenia (BC) in patients with heart failure (HF). Objectives: This study evaluated the association between BC and prognosis in patients with HF. Methods: This retrospective cohort study enrolled consecutive hospitalised patients with HF. We compared all-cause and cardiovascular mortality between those with and without BC. BC was defined as the combination of any two conditions among leukopaenia, thrombocytopaenia, and anaemia. Propensity score matching and a Cox proportional hazards model were applied. Results: Among 935 hospitalised patients, 103 patients had BC. Patients in the BC group were older (80.0 ± 12.0 vs. 73.4 ± 14.7 years; Conclusion: BC was associated with all-cause mortality but not with cardiovascular mortality in patients with HF. BC is an important risk factor for all-cause mortality in patients with HF.

Indexed as

AnemiaHeart FailureHospitalizationLeukopeniaThrombocytopeniaAgedAged, 80 and overCause of DeathFemaleFollow-Up StudiesHospital MortalityHumansMalePrognosisPropensity ScoreRetrospective Studiesall-cause mortalitybicytopeniablood disorderheart failure

Identifiers

PMID40322052
PMCPMC12047623

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.