ArticleBiomedical optics express2025
Dome-APIC illumination design for high space-bandwidth product analytic imaging.
Article in Biomedical optics express, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Breaking the tradeoff between resolution and field-of-view, while obtaining distortion-free images, can be achieved through computational imaging techniques. A recent approach, Angular Ptychographic Imaging with Close-form method (APIC), has showcased its capability to analytically recover both intricate aberrations and high space-bandwidth product complex optical fields with NA-matching and darkfield illuminations. However, its flat illumination setup limits its ability to efficiently reconstruct a large field-of-view simultaneously with high resolution, owing to the curvature in the wavefront from NA-matching illuminations and the finite beam angle of the Lambertian LED light source. Here, we introduce an illumination framework tailored for APIC consisting of a distant annular LED ring and an LED dome that enables the reconstruction of a larger area with an extended synthetic numerical aperture, consequently enhancing resolution. For a single set of measurements, our new prototype, termed Dome-APIC can reach 620nm resolution with a 10×/0.25 NA objective lens over a field-of-view of 450
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