ArticleBiomedical optics express2025
Multiphoton microscopy at a microwatt level via gain-managed nonlinear amplification and pulse-picking.
Article in Biomedical optics express, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Challenges and Prospects of Using Novel Nonlinear Effects in Multimode Optical Fibers for Multiphoton Endomicroscopy.Diagnostics (Basel, Switzerland) · 2026Review
- Evaluation of a nanosecond dissipative soliton resonance fiber laser for multiphoton microscopy.Scientific reports · 2025Article
- Multiphoton microscopy at a microwatt level via gain-managed nonlinear amplification and pulse-picking.Biomedical optics express · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We introduce a compact, all-fiber laser system with a gain-managed nonlinear (GMN) amplified Yb:fiber oscillator and an integrated pulse-picker. The system delivers 39 fs pulses with peak powers of 0.83 MW and adjustable pulse repetition rates (0.3-15 MHz), enabling multiphoton imaging at remarkably low excitation powers (as low as 66 µW). Its design simplifies integration and enhances experimental flexibility. Compatible with two- and three-photon excitation, but also second harmonic generation microscopy, this versatile system offers precise control of imaging parameters, making it an effective tool for advancing multiphoton microscopy and other imaging techniques across various experimental environments.
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Registered trials
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