Evidence map›Paper›PMID 40321950›Full record

ArticleArXiv2025

Chemical Language Model Linker: blending text and molecules with modular adapters.

Yifan Deng, Spencer S Ericksen, Anthony Gitter

Abstract readPreprint
In one paragraph

Article in ArXiv, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Yifan DengDepartment of Computer Sciences, University of Wisconsin-Madison, Madison, WI 53706, United States.
Spencer S EricksenDrug Development Core, Small Molecule Screening Facility, University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, Madison, WI 53705, United States.
Anthony GitterDepartment of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI 53715, United States.

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Christian Capitini · 1985 to 2026
$142.6M
A Machine Learning Platform for Adaptive Chemical ScreeningR01GM135631 · NIGMS · MORGRIDGE INSTITUTE FOR RESEARCH, INC. · PI GITTER, ANTHONY JAMES · 2020 to 2024
$2.1M
NCI NIH HHS P30 CA014520NIGMS NIH HHS R01 GM135631
6 · The paper itself

Abstract

The development of large language models and multi-modal models has enabled the appealing idea of generating novel molecules from text descriptions. Generative modeling would shift the paradigm from relying on large-scale chemical screening to find molecules with desired properties to directly generating those molecules. However, multi-modal models combining text and molecules are often trained from scratch, without leveraging existing high-quality pretrained models. Training from scratch consumes more computational resources and prohibits model scaling. In contrast, we propose a lightweight adapter-based strategy named

Identifiers

PMID40321950
PMCPMC12047907

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.